Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | KDM4B | O94953 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902126 | 0.94 | NMT1 (0.37) | NMT1FEN1KDM4AKDM4BKDM5C | |
| SCHEMBL9905168 | 0.93 | NMT1 (0.40) | NMT1FEN1KDM4AKDM4BKDM5C | |
| SCHEMBL9111054 | 0.87 | MAPK14 (0.41) | — | |
| SCHEMBL9905458 | 0.87 | MAPK14 (0.31) | — | |
| SCHEMBL9905063 | 0.86 | GRM5 (0.31) | — | |
| SCHEMBL9905014 | 0.85 | — | — | |
| SCHEMBL9905480 | 0.85 | ALOX5AP (0.31) | FEN1 | |
| SCHEMBL9901449 | 0.84 | NMT1 (0.41) | NMT1FEN1KDM4AKDM4BKDM5C | |
| SCHEMBL9901254 | 0.84 | NMT1 (0.39) | NMT1FEN1KDM4AKDM4BKDM5C | |
| SCHEMBL9109694 | 0.84 | NMT1 (0.32) | NMT1KDM4AKDM4BKDM5CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648516-A1 | SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | Confluence Life Sciences, Inc. (US) | 2013-10-16 | — | — | EP | claimed |
| WO-2012078684-A1 | SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | CONFLUENCE LIFE SCIENCES, INC. (US) | 2012-06-14 | — | — | WO | claimed |