Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4B | O94953 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901254 | 0.93 | NMT1 (0.39) | NMT1FEN1KDM4AKDM4BKDM5C | |
| SCHEMBL9905168 | 0.92 | NMT1 (0.40) | NMT1FEN1HTR2AHTR2CSLC6A4 | |
| SCHEMBL9902126 | 0.86 | NMT1 (0.37) | NMT1FEN1KDM4AKDM4BKDM5C | |
| SCHEMBL9110613 | 0.85 | MAPKAPK2 (0.38) | NMT1HTR2AHTR2CSLC6A4HTR2B | |
| SCHEMBL9901297 | 0.85 | BRD4 (0.31) | — | |
| SCHEMBL9904956 | 0.85 | MAPKAPK2 (0.41) | NMT1HTR2AHTR2CSLC6A4HTR2B | |
| SCHEMBL9905341 | 0.84 | NMT1 (0.36) | NMT1FEN1KDM4AKDM4BKDM5C | |
| SCHEMBL9905679 | 0.83 | MAPK14 (0.38) | KDM5BALDH1A1TSHR | |
| SCHEMBL9111410 | 0.83 | NMT1 (0.33) | NMT1HTR2AHTR2CSLC6A4HTR2B | |
| SCHEMBL9901769 | 0.82 | MAOB (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648516-A1 | SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | Confluence Life Sciences, Inc. (US) | 2013-10-16 | — | — | EP | claimed |
| WO-2012078684-A1 | SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | CONFLUENCE LIFE SCIENCES, INC. (US) | 2012-06-14 | — | — | WO | claimed |