Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL14563777 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28873478 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28371980 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28371981 | 0.94 | — | — | |
| Bicarbonate SCHEMBL904477 | 0.94 | — | — | |
| Bicarbonate SCHEMBL10937357 | 0.94 | — | — | |
| Bicarbonate SCHEMBL81418 | 0.94 | — | — | |
| Bicarbonate SCHEMBL8017866 | 0.94 | CA1 (0.62) | CA1CA2CA9ACHEFFAR3 | |
| Bicarbonate SCHEMBL14881195 | 0.94 | CA1 (0.62) | CA1CA2CA9ACHEFFAR3 | |
| Bicarbonate SCHEMBL8017863 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9636665-B2 | Catalyst compositions for converting syngas to produce higher alcohols | GEORGIA TECH RESEARCH CORPORATION (US) | 2017-05-02 | — | — | US | disclosed |
| EP-2648841-B1 | CATALYST COMPOSITIONS FOR CONVERTING SYNGAS TO PRODUCE HIGHER ALCOHOLS | GEORGIA TECH RES INST (US) | 2016-06-15 | — | — | EP | disclosed |
| EP-2648841-A1 | CATALYST COMPOSITIONS FOR CONVERTING SYNGAS TO PRODUCE HIGHER ALCOHOLS | GEORGIA TECH RESEARCH CORPORATION (US) | 2013-10-16 | — | — | EP | disclosed |
| US-20130245328-A1 | CATALYST COMPOSITIONS FOR CONVERTING SYNGAS TO PRODUCE HIGHER ALCOHOLS | GEORGIA TECH RESEARCH CORPORATION (US) | 2013-09-19 | — | — | US | disclosed |
| WO-2012078437-A1 | CATALYST COMPOSITIONS FOR CONVERTING SYNGAS TO PRODUCE HIGHER ALCOHOLS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |