⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL28194648 | 0.89 | CES2 (0.37) | — | |
| Boric Acid SCHEMBL27491138 | 0.89 | CES2 (0.37) | — | |
| Sulfuric Acid SCHEMBL28019611 | 0.84 | CES2 (0.39) | — | |
| SCHEMBL1670337 | 0.75 | — | — | |
| SCHEMBL29352330 | 0.73 | — | — | |
| SCHEMBL45406 | 0.73 | — | — | |
| SCHEMBL3891682 | 0.73 | — | — | |
| SCHEMBL29905653 | 0.73 | — | — | |
| SCHEMBL30125159 | 0.72 | PDK2 (0.39) | — | |
| Bromide SCHEMBL1357794 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102485726-B | Method for preparing 1-R-1'-spiro-(piperidine-4,4'-quinoline)-2'(3'-hydrogen) ketone | WUXI APPTEC CO LTD | 2015-07-01 | — | — | CN | claimed |
| CN-102485726-A | Method for preparing 1-R-1'-spiro-(piperidine-4,4'-quinoline)-2'(3'-hydrogen)ketone | WUXI APPTEC CO LTD | 2012-06-06 | — | — | CN | claimed |
| JP-10081643-A | — | — | None | — | — | JP | disclosed |
| US-20250154193-A1 | STEROID COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Cholesgen (Shanghai) Co., Ltd. (CN) | 2025-05-15 | — | — | US | disclosed |
| CN-116789726-A | Steroid compound, preparation method and application thereof | 珂阑(上海)医药科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| WO-2023143399-A1 | STEROID COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 珂阑(上海)医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |
| WO-2023143398-A1 | STEROID AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 珂阑(上海)医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |
| CN-116514893-A | Steroid compound, preparation method and application thereof | 珂阑(上海)医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-106574008-A | Polycyclo-olefinic block polymers and pervaporation membranes made therefrom | 普罗米鲁斯有限责任公司 | 2017-04-19 | — | — | CN | disclosed |
| US-9139594-B2 | Fused aminodihydropyrimidone derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| EP-2233474-B1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2015-08-05 | — | — | EP | disclosed |
| EP-0440082-B1 | Method for the conversion of fluorinated aromatic compounds using electrophiles | MERCK PATENT GMBH (DE) | 1998-04-15 | — | — | EP | disclosed |
| JP-H1081643-A | PRODUCTION OF ARYLKETONES | TAKEDA CHEM IND LTD | 1998-03-31 | — | — | JP | disclosed |
| EP-0661259-B1 | Substituted (5,6)-dihydronaphthalenyl compounds having retinoid-like activity | BRISTOL MYERS SQUIBB CO (US) | 1997-10-08 | — | — | EP | disclosed |
| CN-1144217-A | Retinoid-like compounds | BRISTOL MYERS SQUIBB CO (US) | 1997-03-05 | — | — | CN | disclosed |
| EP-0661259-A1 | Substituted (5,6)-dihydronaphthalenyl compounds having retinoid-like activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-05 | — | — | EP | disclosed |
| EP-0601156-A1 | CROSS-COUPLING PROCESS OF BORIC ACIDS WITH HALOGENATED COMPOUNDS | MERCK PATENT GmbH (DE) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994000423-A1 | CROSS-COUPLING PROCESS OF BORIC ACIDS WITH HALOGENATED COMPOUNDS | MERCK PATENT GMBH (DE) | 1994-01-06 | — | — | WO | disclosed |
| US-5262556-A | Alkylation or hydroxyalkylation by deprotonation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-11-16 | — | — | US | disclosed |
| EP-0440082-A2 | Method for the conversion of fluorinated aromatic compounds using electrophiles | MERCK PATENT GmbH (DE) | 1991-08-07 | — | — | EP | disclosed |