Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583619 | 0.88 | HDAC1 (0.53) | MEN1KMT2ANAAACES2CES1 | |
| SCHEMBL11583576 | 0.85 | NAAA (0.71) | NAAACES2CES1HPGDALDH1A1 | |
| SCHEMBL11584829 | 0.85 | NAAA (0.71) | NAAACES2CES1HPGDALDH1A1 | |
| SCHEMBL8980055 | 0.85 | NAAA (0.60) | NAAACES2CES1HPGDHDAC3 | |
| SCHEMBL10988822 | 0.84 | NAAA (0.69) | NAAACES2CES1HPGDALDH1A1 | |
| SCHEMBL4323133 | 0.82 | NAAA (0.76) | RECQLMEN1KMT2ANAAAHDAC3 | |
| SCHEMBL12018336 | 0.80 | CES1 (0.56) | MEN1KMT2ACES2CES1HPGD | |
| SCHEMBL22149948 | 0.80 | NAAA (0.68) | RECQLMEN1KMT2ANAAAHDAC3 | |
| SCHEMBL20663412 | 0.79 | MAPK1 (0.60) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7300898 | 0.77 | CES1 (0.55) | MEN1KMT2ANAAACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198031-B2 | Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening | MONOGRAM BIOSCIENCES, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20080233602-A1 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. | 2008-09-25 | — | — | US | disclosed |