Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059690 | 0.76 | LMNA (0.30) | — | |
| SCHEMBL4152740 | 0.73 | LMNA (0.43) | ALDH1A1TSHR | |
| SCHEMBL4353330 | 0.72 | — | — | |
| SCHEMBL536385 | 0.72 | — | — | |
| SCHEMBL11316083 | 0.72 | — | — | |
| SCHEMBL27575205 | 0.69 | TDP1 (0.33) | — | |
| SCHEMBL29976862 | 0.68 | — | — | |
| SCHEMBL1090931 | 0.67 | LMNA (0.38) | ALDH1A1TSHR | |
| SCHEMBL13174216 | 0.67 | — | — | |
| Acetone SCHEMBL3875597 | 0.67 | LMNA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198031-B2 | Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening | MONOGRAM BIOSCIENCES, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| EP-1540347-B1 | DETECTING RECEPTOR OLIGOMERIZATION | ACLARA BIOSCIENCES INC (US) | 2009-09-09 | — | — | EP | disclosed |
| US-20080233602-A1 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. | 2008-09-25 | — | — | US | disclosed |