Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | OXTR | P30559 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.45 |
| ▸ | HTRA2 | O43464 | 8/20 | 0.44 |
| ▸ | HTRA1 | Q92743 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13678641 | 0.98 | ALB (0.48) | ALBFOLH1SLC5A2AVPR2OXTR | |
| SCHEMBL9906263 | 0.96 | FOLH1 (0.46) | ALBFOLH1SLC5A2AVPR2OXTR | |
| SCHEMBL14426891 | 0.92 | HTRA2 (0.43) | ALBFOLH1SLC5A2AVPR2OXTR | |
| SCHEMBL9906220 | 0.91 | ALB (0.43) | ALBFOLH1SLC5A2 | |
| SCHEMBL14619878 | 0.91 | ALB (0.46) | ALBFOLH1SLC5A2AVPR2OXTR | |
| SCHEMBL14619873 | 0.91 | FOLH1 (0.43) | ALBFOLH1SLC5A2AVPR2OXTR | |
| SCHEMBL29394402 | 0.89 | ALB (0.54) | ALBFOLH1SLC5A2AVPR2OXTR | |
| SCHEMBL9906144 | 0.89 | ALB (0.43) | ALBFOLH1SLC5A2 | |
| SCHEMBL13780477 | 0.89 | ALB (0.48) | ALBFOLH1SLC5A2AVPR2OXTR | |
| SCHEMBL13780484 | 0.87 | FOLH1 (0.47) | ALBFOLH1SLC5A2AVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198031-B2 | Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening | MONOGRAM BIOSCIENCES, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| EP-1540347-B1 | DETECTING RECEPTOR OLIGOMERIZATION | ACLARA BIOSCIENCES INC (US) | 2009-09-09 | — | — | EP | disclosed |
| US-20090011432-A1 | Detecting and Profiling Molecular Complexes | MONOGRAM BIOSCIENCES, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| US-20080233602-A1 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. | 2008-09-25 | — | — | US | disclosed |
| US-7402397-B2 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. (US) | 2008-07-22 | — | — | US | disclosed |
| US-7255999-B2 | Detection of preferential polypetide in sample; otain sample containing preferential polyeptide, electrophorese, incubate with probe, detect signal from probe and recover polypeptide | MONOGRAM BIOSCIENCES, INC. (US) | 2007-08-14 | — | — | US | disclosed |