Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 10/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9906651 | 0.92 | SPHK2 (0.44) | SPHK2SPHK1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9906631 | 0.89 | SPHK2 (0.39) | SPHK2SPHK1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9906654 | 0.87 | SPHK2 (0.37) | SPHK2SPHK1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9906636 | 0.87 | SPHK1 (0.47) | SPHK2SPHK1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9906639 | 0.85 | SPHK1 (0.41) | SPHK2SPHK1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9906612 | 0.82 | DRD2 (0.46) | KMT2ADRD2MMP13 | |
| SCHEMBL13540766 | 0.82 | SPHK1 (0.45) | SPHK2SPHK1ALDH1A1 | |
| SCHEMBL9906718 | 0.79 | SPHK2 (0.42) | SPHK2SPHK1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13540972 | 0.79 | SPHK1 (0.43) | SPHK2SPHK1ALDH1A1 | |
| SCHEMBL9906670 | 0.77 | MEN1 (0.47) | SPHK2SPHK1KMT2ADRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198303-B2 | Methods of use and compositions for the diagnosis and treatment of infectious diseases | SEQUELLA, INC. (US) | 2012-06-12 | — | — | US | disclosed |