Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17089903 | 0.95 | KMT2A (0.62) | KMT2AEPHX2POLBCYP1A2TOP2A | |
| SCHEMBL12878333 | 0.89 | KMT2A (0.61) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| Beta-Alanine SCHEMBL1883914 | 0.88 | KMT2A (0.64) | KMT2AEPHX2TLR2CYP1A2TOP2A | |
| SCHEMBL20758998 | 0.86 | KMT2A (0.74) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3140809 | 0.85 | KMT2A (0.73) | KMT2AEPHX2TLR2 | |
| SCHEMBL13525077 | 0.85 | KMT2A (0.73) | KMT2AEPHX2TLR2 | |
| SCHEMBL6187733 | 0.85 | KMT2A (0.65) | KMT2AEPHX2 | |
| SCHEMBL14008332 | 0.84 | KMT2A (0.64) | KMT2AEPHX2TLR2 | |
| SCHEMBL12620066 | 0.83 | KMT2A (0.65) | KMT2AEPHX2 | |
| SCHEMBL14490950 | 0.83 | KMT2A (0.55) | KMT2AEPHX2POLBTLR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198230-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2012-06-12 | — | — | US | disclosed |
| US-8198230-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2012-06-12 | — | — | US | disclosed |
| US-20110236344-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-09-29 | — | — | US | disclosed |
| US-20110236344-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-09-29 | — | — | US | disclosed |
| US-7956029-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-06-07 | — | — | US | disclosed |
| US-7956029-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-06-07 | — | — | US | disclosed |
| US-7947647-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947647-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-05-24 | — | — | US | disclosed |
| WO-2010071772-A2 | SYNTHESIS OF 3B-AMINO-5-CHOLESTENE AND RELATED 3B-HALIDES INVOLVING I-STEROID AND RETRO-I-STEROID REARRANGEMENTS | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-06-24 | — | — | WO | disclosed |
| US-20100160657-A1 | SYNTHETIC MIMICS OF MAMMALIAN CELL SURFACE RECEPTORS: METHOD AND COMPOSITIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100160657-A1 | SYNTHETIC MIMICS OF MAMMALIAN CELL SURFACE RECEPTORS: METHOD AND COMPOSITIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100029906-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-02-04 | — | — | US | disclosed |
| US-20100029906-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-02-04 | — | — | US | disclosed |
| US-20090197848-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-08-06 | — | — | US | disclosed |
| US-20090197848-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-08-06 | — | — | US | disclosed |
| US-7514400-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-04-07 | — | — | US | disclosed |
| US-7514400-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160657-A1 | SYNTHETIC MIMICS OF MAMMALIAN CELL SURFACE RECEPTORS: METHOD AND COMPOSITIONS | NR1H4, LDLR, NR1H3 | KMT2A 4399/4885HDAC3 3369/4885HDAC4 4274/4885 |
| US-20090197848-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | MSR1, M6PR, ASGR1 | KMT2A 4116/4885HDAC3 3489/4885HDAC4 3976/4885 |
| US-20100029906-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | MSR1, M6PR, ASGR1 | KMT2A 4116/4885HDAC3 3489/4885HDAC4 3976/4885 |
| US-20110236344-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | MSR1, M6PR, ASGR1 | KMT2A 4116/4885HDAC3 3489/4885HDAC4 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.