Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | PREP | P48147 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | APLNR | P35414 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920336 | 0.89 | ALOX5AP (0.37) | ALOX5APFEN1ERN1CA1CA12 | |
| SCHEMBL5042411 | 0.82 | ALDH1A1 (0.33) | ALOX5APFEN1PREPCA1CA12 | |
| SCHEMBL6904874 | 0.82 | CA1 (0.32) | ALOX5APFEN1PREPCA1CA12 | |
| SCHEMBL5139277 | 0.79 | ALDH1A1 (0.40) | ERN1CA1CA2 | |
| SCHEMBL6907417 | 0.79 | PREP (0.32) | PREPCA1CA12CA9 | |
| SCHEMBL29993848 | 0.77 | CA12 (0.47) | ERN1PREPCA1CA12CA9 | |
| SCHEMBL1620647 | 0.77 | CA12 (0.47) | ERN1PREPCA1CA12CA9 | |
| SCHEMBL14920255 | 0.77 | ALOX5AP (0.36) | ALOX5APFEN1PREP | |
| SCHEMBL18393234 | 0.76 | ERN1 (0.42) | ALOX5APFEN1ERN1CA1CA12 | |
| SCHEMBL17494765 | 0.76 | CA12 (0.46) | ERN1PREPCA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198302-B2 | Anticancer agent having a quinone, quinone prodrug, catechol or catechol prodrug moiety; free of combretastatin A-1 | OXIGENE, INC. (US) | 2012-06-12 | — | — | US | disclosed |