SCHEMBL9906996

SCHEMBL9906996

CC(C)(c1ccc(OP(C)(C)=O)cc1)c1ccc(OP(=O)(Oc2ccccc2)Oc2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.44
TSHR P16473 1/20 0.44
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
SRC P12931 1/20 0.40
ALDH1A1 P00352 5/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
KDM4E B2RXH2 6/20 0.38
POLB P06746 1/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25513744 0.93 CYP3A4 (0.50) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL218852 0.93 CYP3A4 (0.50) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL6472688 0.91 CYP3A4 (0.48) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL1548707 0.91 CYP3A4 (0.48) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL19886573 0.90 MEN1 (0.41) CYP3A4MEN1KMT2ASMN1; SMN2SRC
SCHEMBL9332956 0.90 CYP3A4 (0.50) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL17791905 0.88 TSHR (0.42) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL15257114 0.87 PKM (0.51) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL14900368 0.87 CYP3A4 (0.44) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL23863362 0.86 CYP3A4 (0.41) CYP3A4TSHRMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623795-B2 Method for maintaining antiwear performance of turbine oils containing polymerized amine antioxidants and for improving the deposit formation resistance performance of turbine oils containing monomeric and/or polymeric antioxidants EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-01-07 US disclosed
US-20120142567-A1 METHOD FOR MAINTAINING ANTIWEAR PERFORMANCE OF TURBINE OILS CONTAINING POLYMERIZED AMINE ANTIOXIDANTS AND FOR IMPROVING THE DEPOSIT FORMATION RESISTANCE PERFORMANCE OF TURBINE OILS CONTAINING MONOMERIC AND/OR POLYMERIC ANTIOXIDANTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-06-07 US disclosed
US-20120028861-A1 METHOD FOR IMPROVING THE DEPOSIT FORMATION RESISTANCE PERFORMANCE OF TURBINE OILS CONTAINING AMINE ANTIOXIDANTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-02-02 US disclosed