Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | MMP12 | P39900 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20016726 | 0.83 | MMP2 (0.52) | TDP1MMP2MMP12MMP9MMP1 | |
| SCHEMBL8540180 | 0.82 | MMP2 (0.51) | TDP1MMP2MMP12MMP9MMP1 | |
| SCHEMBL19502542 | 0.80 | DAO (0.65) | TDP1ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL304176 | 0.79 | TDP1 (0.78) | TDP1ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL20286056 | 0.78 | MMP2 (0.48) | TDP1MMP2MMP12MMP9MMP1 | |
| SCHEMBL20016727 | 0.78 | MMP2 (0.48) | TDP1MMP2MMP12MMP9MMP1 | |
| SCHEMBL28207503 | 0.77 | TDP1 (0.75) | TDP1ALDH1A1MAPK1L3MBTL1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28588274 | 0.77 | TDP1 (0.75) | TDP1ALDH1A1MAPK1L3MBTL1KMT2A | |
| Bicarbonate SCHEMBL7699565 | 0.77 | TDP1 (0.75) | TDP1ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL2514087 | 0.77 | MMP2 (0.52) | TDP1MMP2MMP12MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197759-B2 | Bodipy fluorophore dyes useful in the labeling and identification of proteins; highly soluble | MONTANA STATE UNIVERSITY (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197758-B2 | Bodipy fluorophore dyes useful in the labeling and identification of proteins; highly soluble | MONTANA STATE UNIVERSITY (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197759-B2 | Bodipy fluorophore dyes useful in the labeling and identification of proteins; highly soluble | MONTANA STATE UNIVERSITY (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197758-B2 | Bodipy fluorophore dyes useful in the labeling and identification of proteins; highly soluble | MONTANA STATE UNIVERSITY (US) | 2012-06-12 | — | — | US | disclosed |
| US-7833799-B2 | Zwitterionic dyes for labeling in proteomic and other biological analyses | MONTANA STATE UNIVERSITY (US) | 2010-11-16 | — | — | US | disclosed |
| US-7833799-B2 | Zwitterionic dyes for labeling in proteomic and other biological analyses | MONTANA STATE UNIVERSITY (US) | 2010-11-16 | — | — | US | disclosed |
| US-20100203645-A1 | NOVEL ZWITTERIONIC DYES FOR LABELING IN PROTEOMIC AND OTHER BIOLOGICAL ANAYLSES | NATIONAL SCIENCE FOUNDATION | 2010-08-12 | — | — | US | disclosed |
| US-20100203645-A1 | NOVEL ZWITTERIONIC DYES FOR LABELING IN PROTEOMIC AND OTHER BIOLOGICAL ANAYLSES | NATIONAL SCIENCE FOUNDATION | 2010-08-12 | — | — | US | disclosed |
| US-20100036133-A1 | NOVEL ZWITTERIONIC DYES FOR LABELING IN PROTEOMIC AND OTHER BIOLOGICAL ANALYSES | MONTANA STATE UNIVERSITY (US) | 2010-02-11 | — | — | US | disclosed |
| US-20100036133-A1 | NOVEL ZWITTERIONIC DYES FOR LABELING IN PROTEOMIC AND OTHER BIOLOGICAL ANALYSES | MONTANA STATE UNIVERSITY (US) | 2010-02-11 | — | — | US | disclosed |
| US-7582260-B2 | Zwitterionic dyes for labeling in proteomic and other biological analyses | MONTANA STATE UNIVERSITY (US) | 2009-09-01 | — | — | US | disclosed |
| US-7582260-B2 | Zwitterionic dyes for labeling in proteomic and other biological analyses | MONTANA STATE UNIVERSITY (US) | 2009-09-01 | — | — | US | disclosed |
| US-20070259333-A1 | NOVEL ZWITTERIONIC DYES FOR LABELING IN PROTEOMIC AND OTHER BIOLOGICAL ANALYSES | MONTANA STATE UNIVERSITY (US) | 2007-11-08 | — | — | US | disclosed |
| US-20070259333-A1 | NOVEL ZWITTERIONIC DYES FOR LABELING IN PROTEOMIC AND OTHER BIOLOGICAL ANALYSES | MONTANA STATE UNIVERSITY (US) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100203645-A1 | NOVEL ZWITTERIONIC DYES FOR LABELING IN PROTEOMIC AND OTHER BIOLOGICAL ANAYLSES | ACP1, ANXA5, CHAMP1 | TDP1 3114/4885MMP2 1257/4885MMP12 316/4885 |
| US-20100036133-A1 | NOVEL ZWITTERIONIC DYES FOR LABELING IN PROTEOMIC AND OTHER BIOLOGICAL ANALYSES | CHAMP1, ANXA5, ANXA3 | TDP1 3511/4885MMP2 2925/4885MMP12 712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.