SCHEMBL9908470

SCHEMBL9908470

CON[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C=O

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 2/20 0.47
HSD17B10 Q99714 1/20 0.47
ACE P12821 7/20 0.46
ACE2 Q9BYF1 5/20 0.46
GAA P10253 1/20 0.44
DPP4 P27487 1/20 0.43
FAP Q12884 1/20 0.43
DPP8 Q6V1X1 1/20 0.43
DPP9 Q86TI2 1/20 0.43
DPP7 Q9UHL4 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13508877 0.87 ALDH1A1 (0.49) ATML3MBTL1ALDH1A1HSD17B10ACE
SCHEMBL718729 0.83 ACE (0.49) ATML3MBTL1ALDH1A1ACEACE2
SCHEMBL12658560 0.83 DPP4 (0.46) ALDH1A1HSD17B10ACEACE2DPP4
SCHEMBL10605848 0.82 ACE (0.62) ATMACEKMT2A
SCHEMBL10605836 0.82 ACE (0.62) ATMACEKMT2A
SCHEMBL8070929 0.78 ACE (0.51) ACEACE2
SCHEMBL8070930 0.78 ACE (0.51) ACEACE2
SCHEMBL24448607 0.78 DPP4 (0.67) ACEDPP4FAPDPP8DPP9
SCHEMBL16572508 0.78 DPP4 (0.67) ACEDPP4FAPDPP8DPP9
SCHEMBL28852613 0.78 ALDH1A1 (0.50) ATML3MBTL1ALDH1A1HSD17B10ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198364-B2 Poly (vinyl alcohol) polymers, uses and preparation thereof VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) 2012-06-12 US disclosed