Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982145 | 0.93 | TSHR (0.59) | TSHREZH2MEN1KMT2AUSP2 | |
| SCHEMBL29914212 | 0.93 | TSHR (0.59) | TSHREZH2MEN1KMT2AUSP2 | |
| SCHEMBL15093963 | 0.90 | TSHR (0.52) | TSHREZH2MEN1KMT2AUSP2 | |
| SCHEMBL29914217 | 0.90 | TSHR (0.52) | TSHREZH2MEN1KMT2AUSP2 | |
| SCHEMBL6526426 | 0.90 | TSHR (0.55) | TSHREZH2MEN1KMT2AUSP2 | |
| SCHEMBL1953902 | 0.85 | TSHR (0.57) | TSHREZH2MEN1KMT2AUSP2 | |
| SCHEMBL30409767 | 0.85 | TSHR (0.57) | TSHREZH2MEN1KMT2AUSP2 | |
| SCHEMBL15482368 | 0.82 | TSHR (0.53) | TSHREZH2MEN1KMT2AUSP2 | |
| SCHEMBL989495 | 0.81 | TSHR (0.58) | TSHREZH2USP2TDP1SSTR1 | |
| SCHEMBL1022340 | 0.81 | TSHR (0.60) | TSHREZH2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275405-A1 | PROCESS FOR PRODUCING ISOCYANATE USING DIARYL CARBONATE | Asahi Kasei Chemicals Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |