Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.46 |
| ▸ | ADH1B | P00325 | 1/20 | 0.46 |
| ▸ | ADH1C | P00326 | 1/20 | 0.46 |
| ▸ | ADH1A | P07327 | 1/20 | 0.46 |
| ▸ | ADH4 | P08319 | 1/20 | 0.46 |
| ▸ | ADH7 | P40394 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341567 | 1.00 | TSHR (0.57) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL11659167 | 1.00 | TSHR (0.57) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL5983908 | 1.00 | TSHR (0.57) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL7742021 | 1.00 | TSHR (0.57) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL5984690 | 1.00 | TSHR (0.57) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL5279912 | 1.00 | TSHR (0.57) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| Hydrochloric Acid SCHEMBL5984618 | 0.98 | TSHR (0.55) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| Hydrochloric Acid SCHEMBL5595474 | 0.98 | TSHR (0.55) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL3625621 | 0.97 | — | — | |
| SCHEMBL442358 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198461-B2 | Process for the preparation of 3-cyano-1,2,4-triazoles | AMPAC FINE CHEMICALS LLC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20090292122-A1 | PROCESS FOR THE PREPARATION OF CYANO-SUBSTITUTED-NITROGEN-CONTAINING HETEROARYL COMPOUNDS | AMPAC FINE CHEMICALS LLC (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090203737-A1 | Pyrrole Derivatives as Positive Allosteric Modulators of Metabotropic Receptors | ADDEX PHARMA SA (CH) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090292122-A1 | PROCESS FOR THE PREPARATION OF CYANO-SUBSTITUTED-NITROGEN-CONTAINING HETEROARYL COMPOUNDS | ASNS, NCL, NBAS | TSHR 3448/4885ALDH1A1 3567/4885EPHX1 2002/4885 |
| US-20090203737-A1 | Pyrrole Derivatives as Positive Allosteric Modulators of Metabotropic Receptors | GRM5, GRIK5, GRM2 | TSHR 311/4885ALDH1A1 4261/4885EPHX1 3631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.