SCHEMBL9909174

SCHEMBL9909174

Cc1cc(I)c(O)cc1I

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.39
CYP3A4 P08684 2/20 0.36
ALOX15 P16050 2/20 0.36
KDM4E B2RXH2 2/20 0.36
MAPT P10636 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
G6PD P11413 1/20 0.36
CYP2C9 P11712 1/20 0.36
PKM P14618 1/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP2C19 P33261 1/20 0.36
CCR6 P51684 1/20 0.36
HIF1A Q16665 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7871735 0.89 MAPT (0.42) TTRCYP3A4ALOX15KDM4EMAPT
SCHEMBL19669154 0.86 MAPT (0.43) TTRCYP3A4ALOX15KDM4EMAPT
SCHEMBL3892350 0.86 MAPT (0.43) TTRCYP3A4ALOX15KDM4EMAPT
SCHEMBL2589677 0.83 KDM4E (0.55) TTRCYP3A4ALOX15KDM4EMAPT
SCHEMBL19308335 0.83 KDM4E (0.55) TTRCYP3A4ALOX15KDM4EMAPT
SCHEMBL12658291 0.83 KDM4E (0.48) TTRCYP3A4ALOX15KDM4EMAPT
SCHEMBL357190 0.82 TTR (0.44) TTRHPGDHSD17B10ACHESELL
SCHEMBL1685558 0.82 TTR (0.37) TTRCYP3A4ALDH1A1MAPK1TP53
SCHEMBL7873560 0.80 KDM4E (0.50) TTRCYP3A4ALOX15KDM4EMAPT
SCHEMBL31346078 0.77 TTR (0.40) TTRCYP3A4ALOX15KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240210824-A1 CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-06-27 US disclosed
US-20240210824-A1 CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-06-27 US disclosed
US-8198096-B2 Sensor for detection of chemical warfare agents and explosives; polyacetylenes, polyarylenevinylenes; polymers contain hexafluoroisopropanol substituent MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-06-12 US disclosed
US-7943062-B2 Emissive polymers and devices incorporating these polymers MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2011-05-17 US disclosed
US-7662309-B2 increased luminescent lifetimes, quantum yields and amplified emissions; polyacetylenes, polyarylenevinylenes; use in field effect transistors, detection of chemical warfare agents and explosives; solvent resistance, heat resistance MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-02-16 US disclosed
US-7393503-B2 Emissive polymers and devices incorporating these polymers MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240210824-A1 CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SCO2, CBR1, OXGR1 TTR 2982/4885CYP3A4 591/4885ALOX15 914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.