SCHEMBL7871735

SCHEMBL7871735

Cc1cc(O)c(I)cc1I

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.42
ALDH1A1 P00352 4/20 0.42
KDM4E B2RXH2 3/20 0.42
HPGD P15428 2/20 0.42
CYP3A4 P08684 2/20 0.42
ALOX15 P16050 2/20 0.42
MAPK1 P28482 2/20 0.42
HIF1A Q16665 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
G6PD P11413 1/20 0.42
CYP2C9 P11712 1/20 0.42
PKM P14618 1/20 0.42
ALOX12 P18054 1/20 0.42
CYP2C19 P33261 1/20 0.42
CCR6 P51684 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9909174 0.89 TTR (0.39) MAPTALDH1A1KDM4EHPGDCYP3A4
SCHEMBL3892350 0.86 MAPT (0.43) MAPTALDH1A1KDM4EHPGDCYP3A4
SCHEMBL19669154 0.86 MAPT (0.43) MAPTALDH1A1KDM4EHPGDCYP3A4
SCHEMBL19308335 0.83 KDM4E (0.55) MAPTALDH1A1KDM4EHPGDCYP3A4
SCHEMBL2589677 0.83 KDM4E (0.55) MAPTALDH1A1KDM4EHPGDCYP3A4
SCHEMBL1369255 0.78 TTR (0.35) CYP3A4MAPK1TTRTSHR
SCHEMBL70150 0.78 TTR (0.42) ALDH1A1KDM4EHPGDALOX15MAPK1
SCHEMBL12658291 0.78 KDM4E (0.48) MAPTALDH1A1KDM4EHPGDCYP3A4
SCHEMBL18586693 0.77 LMNA (0.52) MAPTALDH1A1KDM4EHPGDCYP3A4
SCHEMBL32665527 0.77 KDM4E (0.37) MAPTALDH1A1KDM4EHPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6320016-B1 X-RAY DETECTABLE ARTICLE MOLDED FROM THERMOPLASTIC COMPOSITION; TOY, MEDICAL EQUIPMENT SUCH AS TUBES, JOINT PARTS BAYER AKTIENGESELLSCHAFT (DE) 2001-11-20 US disclosed