Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9909371 | 0.85 | CTSA (0.34) | CTSAPSMB8PSMB5 | |
| SCHEMBL9909339 | 0.82 | PTPN2 (0.32) | MAOAMAOB | |
| SCHEMBL9110700 | 0.81 | MAPT (0.32) | — | |
| SCHEMBL9909386 | 0.79 | S1PR1 (0.45) | — | |
| SCHEMBL9909350 | 0.67 | S1PR1 (0.43) | PSMB8PSMB5 | |
| SCHEMBL9909370 | 0.66 | S1PR1 (0.36) | PSMB8PSMB5 | |
| SCHEMBL9909383 | 0.66 | CETP (0.35) | CTSA | |
| SCHEMBL9112786 | 0.66 | MAPT (0.33) | — | |
| SCHEMBL13037458 | 0.66 | ERN1 (0.46) | MAOAMAOB | |
| SCHEMBL9909365 | 0.66 | NPC1 (0.41) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142640-A1 | ALKYNE AND ALKENE DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE-1 RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142640-A1 | ALKYNE AND ALKENE DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE-1 RECEPTOR MODULATORS | S1PR1, S1PR3, S1PR2 | MAOA 3370/4885MAOB 2856/4885CTSA 2054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.