SCHEMBL9909443

SCHEMBL9909443

CCCCOC1C(OC(C)=O)[C@@H](SCC)OC2COC(c3ccccc3)O[C@H]21

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.43
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
SELP P16109 1/20 0.37
TSHR P16473 1/20 0.34
PPP5C P53041 1/20 0.33
ALDH1A1 P00352 1/20 0.32
BCHE P06276 3/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPK1 P28482 1/20 0.31
HPGD P15428 1/20 0.30
ATM Q13315 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15197977 1.00 L3MBTL1 (0.43) L3MBTL1KMT2AMEN1SELPTSHR
SCHEMBL17550995 1.00 L3MBTL1 (0.43) L3MBTL1KMT2AMEN1SELPTSHR
SCHEMBL9909432 1.00 L3MBTL1 (0.43) L3MBTL1KMT2AMEN1SELPTSHR
SCHEMBL10073953 0.90 L3MBTL1 (0.47) L3MBTL1KMT2AMEN1SELPPPP5C
SCHEMBL17636518 0.90 L3MBTL1 (0.47) L3MBTL1KMT2AMEN1SELPPPP5C
SCHEMBL9908823 0.89 L3MBTL1 (0.54) L3MBTL1KMT2AMEN1SELPTSHR
SCHEMBL535106 0.89 L3MBTL1 (0.54) L3MBTL1KMT2AMEN1SELPTSHR
SCHEMBL20626555 0.89 L3MBTL1 (0.54) L3MBTL1KMT2AMEN1SELPTSHR
SCHEMBL9110670 0.89 L3MBTL1 (0.54) L3MBTL1KMT2AMEN1SELPTSHR
SCHEMBL15196691 0.89 L3MBTL1 (0.54) L3MBTL1KMT2AMEN1SELPTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120142560-A1 HEPARAN SULFATE SYNTHESIS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2012-06-07 US disclosed