SCHEMBL9909449

SCHEMBL9909449

Cc1ccnc(C(=N)NCl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UHRF1 Q96T88 1/20 0.42
CCR1 P32246 1/20 0.42
CCR5 P51681 1/20 0.42
CCR8 P51685 1/20 0.42
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
KDM4E B2RXH2 1/20 0.39
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
PLAU P00749 1/20 0.37
CTSA P10619 2/20 0.36
CSF1R P07333 1/20 0.36
FLT3 P36888 1/20 0.36
FDPS P14324 1/20 0.36
METAP2 P50579 1/20 0.35
POLB P06746 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1581023 0.85 UHRF1 (0.45) UHRF1CCR1CCR5CCR8KMT2A
SCHEMBL21475739 0.83 UHRF1 (0.43) UHRF1CCR1CCR5CCR8KMT2A
SCHEMBL15908508 0.83 KMT2A (0.45) UHRF1CCR1CCR5CCR8KMT2A
SCHEMBL9909447 0.77 KDM4E (0.56) KMT2AMEN1KDM4ENPC1RAB9A
SCHEMBL8153950 0.75 PLAU (0.48) UHRF1CCR1CCR5CCR8KMT2A
Hydrochloric Acid SCHEMBL22583256 0.73 PLAU (0.47) UHRF1CCR1CCR5CCR8KMT2A
SCHEMBL9909446 0.72 CCR1 (0.40) CCR1CCR5CCR8KMT2AMEN1
SCHEMBL14344860 0.72 KMT2A (0.45) UHRF1CCR1CCR5CCR8KMT2A
SCHEMBL3855482 0.71 UHRF1 (0.52) UHRF1CCR1CCR5CCR8KMT2A
SCHEMBL3855479 0.71 UHRF1 (0.52) UHRF1CCR1CCR5CCR8KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9150601-B2 Blue-light-emitting iridium complex, iridium complex monomer, phosphorus polymer, and organic electroluminescence device using same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-10-06 US disclosed
US-20120138917-A1 BLUE-LIGHT-EMITTING IRIDIUM COMPLEX, IRIDIUM COMPLEX MONOMER, PHOSPHORUS POLYMER, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120138917-A1 BLUE-LIGHT-EMITTING IRIDIUM COMPLEX, IRIDIUM COMPLEX MONOMER, PHOSPHORUS POLYMER, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME IPMK, INTS9, ITK UHRF1 4204/4885CCR1 3570/4885CCR5 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.