SCHEMBL9909447

SCHEMBL9909447

CN(C)c1ccnc(C(=N)NCl)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.56
ALDH1A1 P00352 3/20 0.56
CHRM5 P08912 1/20 0.35
CHKA P35790 1/20 0.35
MAPT P10636 3/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
APP P05067 2/20 0.34
MAPK1 P28482 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 1/20 0.34
MITF O75030 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
HPGD P15428 1/20 0.34
SNCA P37840 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9108412 0.77 ALDH1A1 (0.61) KDM4EALDH1A1CHRM5CHKAMAPT
SCHEMBL9909449 0.77 UHRF1 (0.42) KDM4EALDH1A1MAPTNPC1RAB9A
SCHEMBL9909435 0.75 P4HTM (0.38) KDM4EALDH1A1MAPTNPC1RAB9A
SCHEMBL30209742 0.72 KDM4E (1.00) KDM4EALDH1A1CHRM5CHKAMAPT
SCHEMBL1716682 0.72 KDM4E (1.00) KDM4EALDH1A1CHRM5CHKAMAPT
SCHEMBL12256869 0.72 ALDH1A1 (0.73) KDM4EALDH1A1CHRM5CHKAMAPT
SCHEMBL30209724 0.71 ALDH1A1 (0.67) KDM4EALDH1A1MAPTNPC1MAPK1
SCHEMBL12591131 0.71 ALDH1A1 (0.67) KDM4EALDH1A1MAPTNPC1MAPK1
SCHEMBL2464624 0.70 KDM4E (0.65) KDM4EALDH1A1MAPTNPC1RAB9A
SCHEMBL8861151 0.68 KDM4E (0.67) KDM4EALDH1A1CHRM5CHKAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9150601-B2 Blue-light-emitting iridium complex, iridium complex monomer, phosphorus polymer, and organic electroluminescence device using same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-10-06 US disclosed
US-20120138917-A1 BLUE-LIGHT-EMITTING IRIDIUM COMPLEX, IRIDIUM COMPLEX MONOMER, PHOSPHORUS POLYMER, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120138917-A1 BLUE-LIGHT-EMITTING IRIDIUM COMPLEX, IRIDIUM COMPLEX MONOMER, PHOSPHORUS POLYMER, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME IPMK, INTS9, ITK KDM4E 1932/4885ALDH1A1 1529/4885CHRM5 1812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.