⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21690694 | 0.86 | DRD4 (0.31) | — | |
| SCHEMBL24974308 | 0.79 | GRIN2D (0.38) | — | |
| SCHEMBL23309161 | 0.73 | PIK3CD (0.44) | — | |
| SCHEMBL24808386 | 0.71 | — | — | |
| SCHEMBL24496621 | 0.69 | HSD17B10 (0.39) | — | |
| SCHEMBL2695102 | 0.69 | NEK2 (0.31) | — | |
| SCHEMBL10440099 | 0.69 | NEK2 (0.31) | — | |
| SCHEMBL12727657 | 0.68 | — | — | |
| SCHEMBL9910016 | 0.68 | — | — | |
| SCHEMBL12384784 | 0.67 | OPRD1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| US-9790231-B2 | Chromane and chromene derivatives and their use as CRAC modulators | LUPIN LIMITED (IN) | 2017-10-17 | — | — | US | disclosed |
| US-8198299-B2 | Cycloalkylidene and heterocycloalkylidene inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20120045412-A1 | CYCLOALKYLIDENE AND HETEROCYCLOALKYLIDENE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-02-23 | — | — | US | disclosed |