SCHEMBL9910097

SCHEMBL9910097

CCc1oc(-c2ccc(C(=O)c3ccccc3)cc2)nc1CCOc1ccc2c(c1)CCC2

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.60
PPARA Q07869 18/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9910118 0.86 PPARG (0.56) PPARGPPARA
SCHEMBL9910223 0.86 PPARA (0.55) PPARGPPARA
SCHEMBL25955306 0.86 PPARA (0.65) PPARGPPARA
SCHEMBL25955555 0.86 PPARA (0.65) PPARGPPARA
SCHEMBL31539172 0.86 PPARA (0.55) PPARGPPARA
SCHEMBL25955546 0.86 PPARA (0.55) PPARGPPARA
SCHEMBL9910023 0.85 PPARG (0.70) PPARGPPARA
SCHEMBL12601081 0.84 PPARA (0.58) PPARGPPARA
SCHEMBL9910307 0.83 PPARG (0.88) PPARGPPARA
SCHEMBL13063361 0.83 PPARG (0.88) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012074980-A2 METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISORDERS AND LIVER DISORDERS USING INDANE ACETIC ACID DERIVATIVES DARA BIOSCIENCES, INC. (US) 2012-06-07 WO disclosed