SCHEMBL9910223

SCHEMBL9910223

CCc1oc(-c2ccc(O)cc2)nc1CCOc1ccc2c(c1)CCC2

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.55
PPARG P37231 18/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25955555 0.92 PPARA (0.65) PPARAPPARG
SCHEMBL25955306 0.92 PPARA (0.65) PPARAPPARG
SCHEMBL31539172 0.92 PPARA (0.55) PPARAPPARG
SCHEMBL25955546 0.92 PPARA (0.55) PPARAPPARG
SCHEMBL12601081 0.90 PPARA (0.58) PPARAPPARG
SCHEMBL9910118 0.88 PPARG (0.56) PPARAPPARG
SCHEMBL9910097 0.86 PPARG (0.60) PPARAPPARG
SCHEMBL30515185 0.84 PPARA (0.61) PPARAPPARG
SCHEMBL9910041 0.82 PPARA (0.71) PPARAPPARG
SCHEMBL13049359 0.82 PPARA (0.71) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012074980-A2 METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISORDERS AND LIVER DISORDERS USING INDANE ACETIC ACID DERIVATIVES DARA BIOSCIENCES, INC. (US) 2012-06-07 WO disclosed
WO-2010141696-A1 METHODS OF TREATING OR PREVENTING PSORIASIS, AND/OR ALZHEIMER'S DISEASE USING INDANE ACETIC ACID DERIVATIVES DARA BIOSCIENCES, INC. (US) 2010-12-09 WO disclosed