⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14214971 | 0.81 | — | — | |
| SCHEMBL11748933 | 0.81 | — | — | |
| SCHEMBL13784329 | 0.73 | THRB (0.36) | — | |
| SCHEMBL18726565 | 0.71 | — | — | |
| SCHEMBL17366329 | 0.71 | — | — | |
| SCHEMBL12584840 | 0.71 | — | — | |
| SCHEMBL15039695 | 0.71 | — | — | |
| SCHEMBL18062291 | 0.71 | — | — | |
| SCHEMBL13071397 | 0.71 | — | — | |
| SCHEMBL13825183 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307342-B1 | DIGLYCIDIC ETHER DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2017-06-21 | — | — | EP | disclosed |
| US-20170158606-A1 | FLUORINE-CONTAINING COMPOUND, SUBSTRATE FOR PATTERN FORMATION, PHOTODEGRADABLE COUPLING AGENT, PATTERN FORMATION METHOD, AND COMPOUND | KANAGAWA UNIVERSITY (JP) | 2017-06-08 | — | — | US | disclosed |
| US-20170106065-A1 | Combination Therapy for Treating Cancer with a Poxvirus Expressing a Tumor Antigen and an Antagonist of TIM-3 | BAVARIAN NORDIC A/S (DK) | 2017-04-20 | — | — | US | disclosed |
| WO-2014066506-A2 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | CLEAVE BIOSCIENCES, INC. (US) | 2014-05-01 | — | — | WO | disclosed |
| US-20120142775-A1 | TREATMENT OF NEURODEGENERATIVE CONDITIONS | BTG INTERNATIONAL LIMITED (GB) | 2012-06-07 | — | — | US | disclosed |
| US-20100121041-A1 | METHOD FOR PRODUCTION OF SUGAR OXAZOLINE DERIVATIVE | SEIKAGAKU CORPORATION (JP) | 2010-05-13 | — | — | US | disclosed |
| US-20080069811-A1 | Fsh and Fsh Receptor Modulator Compositions and Methods for Inhibiting Osteclastic Bone Resorption and Bone Loss in Osteoporosis | MOUNT SINAI SCHOOL OF MEDICINCE OF NEW YORK UIVERSITY (NY) | 2008-03-20 | — | — | US | disclosed |