SCHEMBL9912384

SCHEMBL9912384

COOCc1cc(C(=O)OC)cc(-c2nc(-c3ccccc3O)nc(-c3ccccc3N=O)n2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.42
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
NPSR1 Q6W5P4 5/20 0.42
POLB P06746 1/20 0.42
HPGD P15428 4/20 0.41
GAA P10253 3/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 4/20 0.38
KDM4A O75164 1/20 0.37
ALOX15 P16050 3/20 0.37
HSD17B10 Q99714 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ADORA2A P29274 2/20 0.34
TSHR P16473 2/20 0.33
EGFR P00533 2/20 0.33
THRB P10828 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609316 0.92 MAPT (0.48) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL15417604 0.79 MAPT (0.55) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9609305 0.78 MAPT (0.49) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9912394 0.75 EGFR (0.46) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608510 0.74 MAPT (0.54) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608524 0.73 KMT2A (0.50) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9609329 0.73 MAPT (0.46) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL12829543 0.72 EGFR (0.54) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608487 0.72 MEN1 (0.60) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608519 0.71 MAPT (0.47) MAPTMEN1KMT2ANPSR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460799-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM Corporation (JP) 2012-06-06 EP disclosed