Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846890 | 0.79 | HPGD (0.49) | NFE2L2MAPTALDH1A1KMT2AHTT | |
| SCHEMBL846889 | 0.79 | HPGD (0.49) | NFE2L2MAPTALDH1A1KMT2AHTT | |
| SCHEMBL3119611 | 0.75 | CYP2A6 (0.42) | MAPTALDH1A1POLBL3MBTL1KMT2A | |
| SCHEMBL29688801 | 0.75 | CYP2A6 (0.42) | MAPTALDH1A1POLBL3MBTL1KMT2A | |
| SCHEMBL9741686 | 0.75 | CSNK2A1 (0.55) | MAPTALDH1A1POLBKMT2AHTT | |
| SCHEMBL15066436 | 0.73 | PARP1 (0.44) | ALDH1A1KMT2ASMN1; SMN2TDP1HPGD | |
| SCHEMBL27910231 | 0.73 | CSNK2A1 (0.39) | NFE2L2KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL11023700 | 0.71 | NFE2L2 (0.69) | NFE2L2MAPTALDH1A1POLBALOX12 | |
| SCHEMBL11023706 | 0.71 | NFE2L2 (0.69) | NFE2L2MAPTALDH1A1POLBALOX12 | |
| SCHEMBL12124270 | 0.70 | KMT2A (0.41) | KMT2AHTTNPSR1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198458-B2 | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-12 | — | — | US | disclosed |