Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17131758 | 0.88 | ELANE (0.45) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL17131747 | 0.88 | MAPT (0.46) | MAPTRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL14996055 | 0.85 | ELANE (0.50) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL650639 | 0.85 | ELANE (0.50) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL17617137 | 0.85 | ELANE (0.50) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL17131756 | 0.83 | GSK3B (0.43) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL13750796 | 0.83 | MGLL (0.45) | MAPTRAB9AALDH1A1LMNAELANE | |
| SCHEMBL14791147 | 0.83 | PPARA (0.53) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL17122045 | 0.83 | PPARA (0.53) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL12691162 | 0.83 | MGLL (0.45) | MAPTRAB9AALDH1A1LMNAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560893-B1 | PHOTOCHROMIC COMPOSITIONS AND LIGHT TRANSMISSIBLE ARTICLES | ADVANCED POLYMERIK PTY LTD (AU) | 2012-06-06 | — | — | EP | disclosed |