SCHEMBL9912920

SCHEMBL9912920

Cc1cccc(N(c2ccccc2)c2cccc(-n3c4ccc(N(c5ccccc5)c5cccc(C)c5)cc4c4cc(N(c5ccccc5)c5cccc(C)c5)ccc43)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.37
HTR7 P34969 1/20 0.36
KDM4E B2RXH2 2/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GAA P10253 3/20 0.35
GFER P55789 1/20 0.35
NOTUM Q6P988 1/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
ALDH1A1 P00352 4/20 0.34
MAPT P10636 4/20 0.34
PKM P14618 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
RAB9A P51151 1/20 0.34
FGFR1 P11362 1/20 0.33
APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1144028 0.96 KDM4E (0.41) SMN1; SMN2HTR7KDM4EATML3MBTL1
SCHEMBL9912939 0.96 TDP1 (0.35) SMN1; SMN2HTR7L3MBTL1GAAGFER
SCHEMBL9912944 0.93 ALDH1A1 (0.34) SMN1; SMN2HTR7KDM4EATML3MBTL1
SCHEMBL9912915 0.93 KDM4E (0.37) SMN1; SMN2KDM4EATML3MBTL1GAA
SCHEMBL9912968 0.93 KDM4E (0.37) SMN1; SMN2HTR7KDM4EATML3MBTL1
SCHEMBL9912964 0.93 KDM4E (0.37) SMN1; SMN2HTR7KDM4EATML3MBTL1
SCHEMBL9912892 0.93 KDM4E (0.37) SMN1; SMN2HTR7KDM4EATML3MBTL1
SCHEMBL9912922 0.91 KDM4E (0.42) SMN1; SMN2KDM4EATML3MBTL1GAA
SCHEMBL9912940 0.90 POLB (0.34) SMN1; SMN2KDM4EATML3MBTL1GAA
SCHEMBL9912874 0.90 POLB (0.34) SMN1; SMN2HTR7KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198801-B2 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed
US-8198801-B2 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed