SCHEMBL9912925

SCHEMBL9912925

COc1cccc(N(c2cccc(-n3c4ccc(N(c5cccc(OC)c5)c5ccc6ccccc6c5)cc4c4cc(N(c5cccc(OC)c5)c5ccc6ccccc6c5)ccc43)c2)c2ccc3ccccc3c2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
CYP1A2 P05177 2/20 0.40
CYP2A6 P11509 1/20 0.40
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPT P10636 2/20 0.39
HTT P42858 2/20 0.39
THRB P10828 1/20 0.37
USP2 O75604 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
FGFR1 P11362 2/20 0.35
RPS6KB1 P23443 1/20 0.35
NTRK1 P04629 1/20 0.34
IGF1R P08069 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9912953 0.94 MTNR1A (0.42) MTNR1AMTNR1BCYP1A2CYP2A6KDM4E
SCHEMBL9912929 0.93 CYP1A2 (0.40) MTNR1AMTNR1BCYP1A2CYP2A6KDM4E
SCHEMBL9912897 0.93 MTNR1A (0.43) MTNR1AMTNR1BCYP1A2CYP2A6KDM4E
SCHEMBL9912985 0.92 MTNR1A (0.42) MTNR1AMTNR1BCYP1A2CYP2A6KDM4E
SCHEMBL9912924 0.91 KDM4E (0.44) MTNR1AMTNR1BCYP1A2KDM4ESMN1; SMN2
SCHEMBL9912936 0.89 KDM4E (0.41) MTNR1AMTNR1BCYP1A2KDM4ESMN1; SMN2
SCHEMBL12856848 0.89 KDM4E (0.49) MTNR1AMTNR1BCYP1A2KDM4ESMN1; SMN2
SCHEMBL9912923 0.87 KDM4E (0.36) CYP1A2KDM4ESMN1; SMN2MAPTHTT
SCHEMBL9912928 0.87 SMN1; SMN2 (0.40) MTNR1AMTNR1BCYP1A2KDM4ESMN1; SMN2
SCHEMBL9912914 0.86 MTNR1A (0.39) MTNR1AMTNR1BCYP1A2CYP2A6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198801-B2 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed
US-8198801-B2 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed