Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.82 |
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586348 | 0.92 | NR3C1 (0.83) | NR3C1PGRAR | |
| SCHEMBL3592736 | 0.90 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL3586154 | 0.86 | NR3C1 (0.84) | NR3C1PGRAR | |
| SCHEMBL3588907 | 0.86 | NR3C1 (0.88) | NR3C1PGRAR | |
| SCHEMBL3590764 | 0.84 | NR3C1 (0.62) | NR3C1PGRAR | |
| SCHEMBL3589536 | 0.82 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL9913415 | 0.81 | NR3C1 (0.84) | NR3C1PGRAR | |
| SCHEMBL3581567 | 0.81 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL3594195 | 0.81 | NR3C1 (0.84) | NR3C1PGRAR | |
| SCHEMBL3600990 | 0.81 | NR3C1 (0.62) | NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198311-B2 | Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-06-12 | — | — | US | disclosed |