SCHEMBL991362

SCHEMBL991362

CC(C)c1ccccc1OC(=O)Oc1ccccc1C(C)C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C19 P33261 1/20 0.50
CES2 O00748 1/20 0.48
HPGD P15428 3/20 0.47
KDM4E B2RXH2 2/20 0.47
HSD17B10 Q99714 2/20 0.47
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
GABRA1 P14867 3/20 0.45
GABRB2 P47870 2/20 0.45
LPAR1 Q92633 1/20 0.44
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KCNK3 O14649 1/20 0.43
KCNK9 Q9NPC2 1/20 0.43
GABRB1 P18505 2/20 0.42
PTGS1 P23219 2/20 0.41
BLM P54132 2/20 0.41
FAAH O00519 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL720572 0.88 KDM4E (0.55) TSHRCYP1A2CYP2C19CES2HPGD
SCHEMBL6398525 0.86 TSHR (0.49) TSHRCYP1A2CYP2C19CES2HPGD
SCHEMBL9979219 0.86 TSHR (0.49) TSHRCYP1A2CYP2C19CES2HPGD
Hydrogen Peroxide SCHEMBL8008634 0.86 KDM4E (0.58) TSHRCYP1A2CYP2C19CES2HPGD
SCHEMBL6895920 0.86 TSHR (0.47) TSHRCYP1A2CYP2C19CES2KMT2A
SCHEMBL6895916 0.86 CYP1A2 (0.47) TSHRCYP1A2CYP2C19CES2HPGD
SCHEMBL6896430 0.86 CYP1A2 (0.44) TSHRCYP1A2CYP2C19CES2HPGD
SCHEMBL11170809 0.84 TSHR (0.49) TSHRCYP1A2CYP2C19CES2HPGD
SCHEMBL24712460 0.84 ELANE (0.50) TSHRCYP1A2CYP2C19CES2KMT2A
SCHEMBL5836784 0.84 CYP1A2 (0.48) TSHRCYP1A2CYP2C19CES2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0066546-B1 EPOXIDE RESIN COMPOSITIONS CONTAINING ESTERS AS A DILUTING AGENT AND HARDENING ACCELERATORS CIBA-GEIGY AG (CH) 1985-12-18 EP claimed
US-4414377-A Epoxide resin compositions containing esters as diluents and cure accelerators CIBA-GEIGY CORPORATION (US) 1983-11-08 US claimed
EP-0066546-A2 Epoxide resin compositions containing esters as a diluting agent and hardening accelerators CIBA-GEIGY AG (CH) 1982-12-08 EP claimed
EP-3795561-B1 METHOD FOR PRODUCING CARBAMATE AND METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2024-11-06 EP disclosed
CN-115838452-A Resin, preparation method, resin composition, optical film, adhesive and polymer 华为技术有限公司 2023-03-24 CN disclosed
US-11352319-B2 Method for producing carbamate and method for producing isocyanate ASAHI KASEI KABUSHIKI KAISHA (JP) 2022-06-07 US disclosed
US-11306055-B2 Isocyanate production method ASAHI KASEI KABUSHIKI KAISHA (JP) 2022-04-19 US disclosed
EP-3626704-B1 ISOCYANATE PRODUCTION METHOD ASAHI CHEMICAL IND (JP) 2021-11-24 EP disclosed
US-20210179548-A1 METHOD FOR PRODUCING CARBAMATE AND METHOD FOR PRODUCING ISOCYANATE ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-06-17 US disclosed
US-10968168-B2 Isocyanate production method ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-04-06 US disclosed
EP-3795561-A1 METHOD FOR PRODUCING CARBAMATE AND METHOD FOR PRODUCING ISOCYANATE Asahi Kasei Kabushiki Kaisha (JP) 2021-03-24 EP disclosed
US-20070208159-A1 POLY(ARYLENE ETHER) BLOCK COPOLYMER COMPOSITIONS, METHODS, AND ARTICLES GENERAL ELECTRIC COMPANY (US) 2007-09-06 US disclosed
US-20070208145-A1 POLY(ARYLENE ETHER) BLOCK COPOLYMER COMPOSITIONS, METHODS, AND ARTICLES GENERAL ELECTRIC COMPANY (US) 2007-09-06 US disclosed
US-20070208144-A1 POLY(ARYLENE ETHER) BLOCK COPOLYMER COMPOSITIONS, METHODS, AND ARTICLES GENERAL ELECTRIC COMPANY (US) 2007-09-06 US disclosed
EP-0066546-B1 EPOXIDE RESIN COMPOSITIONS CONTAINING ESTERS AS A DILUTING AGENT AND HARDENING ACCELERATORS CIBA-GEIGY AG (CH) 1985-12-18 EP disclosed
US-4414377-A Epoxide resin compositions containing esters as diluents and cure accelerators CIBA-GEIGY CORPORATION (US) 1983-11-08 US disclosed
EP-0066546-A2 Epoxide resin compositions containing esters as a diluting agent and hardening accelerators CIBA-GEIGY AG (CH) 1982-12-08 EP disclosed
US-4202833-A INTERMEDIATES TO BISPHENOL CARBONATES THE UPJOHN COMPANY (US) 1980-05-13 US disclosed
US-4200763-A CHEMICAL INTERMEDIATE THE UPJOHN COMPANY (US) 1980-04-29 US disclosed
US-4164510-A METAL PHTHALOCYANINE, TERT-ALKYL PEROXIDE AS CATALYST THE UPJOHN COMPANY (US) 1979-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352319-B2 Method for producing carbamate and method for producing isocyanate CPS1, CA7, CA4 TSHR 4164/4885CYP1A2 502/4885CYP2C19 557/4885
US-20210179548-A1 METHOD FOR PRODUCING CARBAMATE AND METHOD FOR PRODUCING ISOCYANATE CPS1, CA7, CA4 TSHR 4164/4885CYP1A2 502/4885CYP2C19 557/4885
US-10968168-B2 Isocyanate production method IDH3A, ALKBH3, CPS1 TSHR 4661/4885CYP1A2 184/4885CYP2C19 203/4885
US-11306055-B2 Isocyanate production method CA7, IDH3A, CA4 TSHR 4368/4885CYP1A2 398/4885CYP2C19 320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.