Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10344219 | 0.88 | ALDH1A1 (0.56) | TSHRALDH1A1KMT2AMEN1P2RX4 | |
| SCHEMBL6895920 | 0.85 | TSHR (0.47) | TSHRCYP1A2CYP2C19CES2KMT2A | |
| SCHEMBL991362 | 0.84 | TSHR (0.50) | TSHRALDH1A1CYP1A2CYP2C19CES2 | |
| SCHEMBL1790655 | 0.81 | ALDH1A1 (0.49) | TSHRALDH1A1LMNAP2RX4KDM4E | |
| SCHEMBL25990012 | 0.80 | LMNA (0.50) | ALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL30417301 | 0.80 | LMNA (0.50) | ALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL11179139 | 0.80 | ALDH1A1 (0.44) | TSHRALDH1A1CYP1A2CYP2C19CES2 | |
| SCHEMBL11170890 | 0.80 | ALDH1A1 (0.56) | TSHRALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL25298413 | 0.79 | PTGDR2 (0.47) | TSHRALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL10344225 | 0.79 | ALDH1A1 (0.50) | TSHRALDH1A1P2RX4KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4403056-A | POLYVINYL CHLORIDE PLASTICIZER | STAUFFER CHEMICAL COMPANY (US) | 1983-09-06 | — | — | US | disclosed |