Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 5/20 | 0.43 |
| ▸ | BID | P55957 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9913891 | 1.00 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| Hydrochloric Acid SCHEMBL9277967 | 0.98 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| Hydrochloric Acid SCHEMBL9277971 | 0.98 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| SCHEMBL15573563 | 0.82 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| SCHEMBL13478355 | 0.82 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| SCHEMBL23951657 | 0.79 | TEAD4 (0.43) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| SCHEMBL16622980 | 0.79 | MAPT (0.43) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| SCHEMBL23951609 | 0.79 | KDM1A (0.42) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL30230283 | 0.79 | TEAD4 (0.43) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| SCHEMBL16761863 | 0.79 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012072512-A1 | N-CYCLOBUTYL-IMIDAZOPYRIDINE OR -PYRAZOLOPYRIDINE CARBOXAMIDES AS TRPV1 ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2012-06-07 | — | — | WO | disclosed |