Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | FURIN | P09958 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014799 | 0.95 | EPHX2 (0.42) | FFAR4EPHX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3037790 | 0.91 | EPHX2 (0.48) | FFAR4EPHX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19510585 | 0.86 | FFAR4 (0.40) | FFAR4EPHX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23897757 | 0.83 | MCHR1 (0.39) | FFAR4EPHX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20064173 | 0.82 | FFAR4 (0.40) | FFAR4EPHX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2679228 | 0.81 | HRH1 (0.55) | EPHX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3121707 | 0.81 | EPHX2 (0.40) | FFAR4EPHX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12078197 | 0.81 | GRM5 (0.41) | FFAR4EPHX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14300800 | 0.81 | GRM5 (0.40) | FFAR4EPHX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13078055 | 0.80 | FFAR4 (0.42) | FFAR4EPHX2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069863-A1 | 1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |
| WO-2012072512-A1 | N-CYCLOBUTYL-IMIDAZOPYRIDINE OR -PYRAZOLOPYRIDINE CARBOXAMIDES AS TRPV1 ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2012-06-07 | — | — | WO | disclosed |