Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (Z)-1,2-Diphenylethene SCHEMBL991412 | 1.00 | PPARA (0.58) | PPARAALDH1A1GAAEGFRHDAC3 | |
| Stearic Acid SCHEMBL5009636 | 0.90 | PPARA (0.57) | PPARAALDH1A1EGFRAKR1B1LMNA | |
| Cinnamic Acid SCHEMBL19244293 | 0.90 | HDAC3 (0.63) | PPARAALDH1A1GAAEGFRHDAC3 | |
| (Z)-1,2-Diphenylethene SCHEMBL27882892 | 0.88 | PPARA (0.66) | PPARAALDH1A1GAAHDAC3PAM | |
| (Z)-1,2-Diphenylethene SCHEMBL27882891 | 0.88 | PPARA (0.66) | PPARAALDH1A1GAAHDAC3PAM | |
| (E)-3-Stilbenol SCHEMBL27979211 | 0.87 | PPARA (0.51) | PPARAHDAC3AKR1B1 | |
| (E)-3,4-Stilbendiol SCHEMBL27882834 | 0.86 | IAPP (0.65) | PPARAPTPN1 | |
| (Z)-1,2-Diphenylethene SCHEMBL27527844 | 0.83 | ALDH1A1 (0.73) | PPARAALDH1A1GAAHDAC3PAM | |
| Nonanoate SCHEMBL1774981 | 0.82 | ALDH1A1 (0.55) | PPARAALDH1A1EGFRAKR1B1LMNA | |
| Biphenyl SCHEMBL27377379 | 0.82 | AKR1B1 (0.56) | PPARAALDH1A1HDAC3AKR1B1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445511-A2 | SKIN REPAIR COMPOSITIONS COMPRISING CIRCADIAN GENE ACTIVATORS AND A SYNERGISTIC COMBINATION OF SIRT1 GENE ACTIVATORS | ELC Management LLC (US) | 2012-05-02 | — | — | EP | disclosed |
| WO-2011005406-A2 | SKIN REPAIR COMPOSITIONS COMPRISING CIRCADIAN GENE ACTIVATORS AND A SYNERGISTIC COMBINATION OF SIRT1 GENE ACTIVATORS | ELC MANAGEMENT LLC (US) | 2011-01-13 | — | — | WO | disclosed |
| EP-2185128-A1 | COSMETIC COMPOSITIONS CONTAINING RESVERATROL DERIVATIVES | ELC Management LLC (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009017866-A1 | COSMETIC COMPOSITIONS CONTAINING RESVERATROL DERIVATIVES | ELC MANAGEMENT LLC (US) | 2009-02-05 | — | — | WO | disclosed |