Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.46 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.46 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.46 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.46 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990252 | 0.90 | SPHK1 (0.45) | MAPK14CSNK1DPRKD3MAP4K4ERBB2 | |
| SCHEMBL990284 | 0.83 | MAPK14 (0.47) | MAPK14CSNK1DEGFRMAPK13MAPK12 | |
| SCHEMBL4837575 | 0.83 | MAPK14 (0.72) | MAPK14CSNK1DERBB2FGFR1MAPK8 | |
| SCHEMBL990654 | 0.83 | MAPK14 (0.55) | MAPK14CSNK1DPRKD3MAP4K4ERBB2 | |
| SCHEMBL5772806 | 0.79 | MAPK14 (0.76) | MAPK14CSNK1DERBB2FGFR1MAPK8 | |
| SCHEMBL989496 | 0.77 | MAPK14 (0.57) | MAPK14CSNK1DPRKD3MAP4K4ERBB2 | |
| SCHEMBL5771351 | 0.77 | MAPK14 (0.71) | MAPK14CSNK1DERBB2FGFR1MAPK8 | |
| SCHEMBL5768867 | 0.77 | MAPK14 (0.71) | MAPK14CSNK1DERBB2FGFR1MAPK8 | |
| SCHEMBL990285 | 0.75 | KDM4E (0.41) | MAPK14CSNK1DERBB2EGFRMAPK13 | |
| Hydrochloric Acid SCHEMBL4833681 | 0.75 | MAPK14 (0.71) | MAPK14CSNK1DERBB2FGFR1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863310-B2 | Kinase inhibitors | ELI LILLY AND COMPANY (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080227839-A1 | Kinase Inhibitors | ELI LILLY AND COMPANY | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227839-A1 | Kinase Inhibitors | ABL1, MAP3K20, MAP3K19 | MAPK14 341/4885CSNK1D 85/4885PRKD3 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.