Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.30 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960304 | 0.80 | BIRC2 (0.35) | PLA2G10PLA2G5ITGB3ITGB2ITGB1 | |
| SCHEMBL24709213 | 0.79 | HTR4 (0.41) | PLA2G10PLA2G5CNR1WNT1GSK3B | |
| SCHEMBL10063507 | 0.75 | HSD17B10 (0.42) | PLA2G10PLA2G5WNT1GSK3BDYRK1A | |
| SCHEMBL1041478 | 0.75 | HSD17B10 (0.42) | PLA2G10PLA2G5WNT1GSK3BDYRK1A | |
| SCHEMBL12004645 | 0.75 | HSD17B10 (0.42) | PLA2G10PLA2G5WNT1GSK3BDYRK1A | |
| SCHEMBL16749946 | 0.75 | HSD17B10 (0.42) | PLA2G10PLA2G5WNT1GSK3BDYRK1A | |
| SCHEMBL20260416 | 0.75 | HSD17B10 (0.42) | PLA2G10PLA2G5WNT1GSK3BDYRK1A | |
| SCHEMBL27147241 | 0.75 | PLA2G10 (0.41) | PLA2G10PLA2G5WNT1GSK3BDYRK1A | |
| SCHEMBL3470166 | 0.75 | PLA2G10 (0.41) | PLA2G10PLA2G5WNT1GSK3BDYRK1A | |
| SCHEMBL3799622 | 0.75 | PLA2G10 (0.41) | PLA2G10PLA2G5WNT1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451776-A2 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011005322-A2 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| EP-1311301-A2 | STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND METHODS FOR PREPARATION THEREOF | Bristol-Myers Squibb Pharma Company (US) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002004030-A2 | STABLE RADIOPHARMACEUTICAL COMPOSITIONS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-01-17 | — | — | WO | disclosed |