Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PPP5C | P53041 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10039979 | 1.00 | EPHX2 (0.38) | EPHX2ALDH1A1ATMESR1TSHR | |
| SCHEMBL13525934 | 1.00 | EPHX2 (0.38) | EPHX2ALDH1A1ATMESR1TSHR | |
| SCHEMBL22945696 | 0.85 | GAA (0.35) | ALDH1A1ATMTSHRCYP1A2 | |
| SCHEMBL31462441 | 0.85 | GAA (0.35) | ALDH1A1ATMTSHRCYP1A2 | |
| SCHEMBL7700042 | 0.84 | EPHX2 (0.39) | EPHX2ALDH1A1ATMTSHRTDP1 | |
| Hydrochloric Acid SCHEMBL28715389 | 0.83 | GAA (0.34) | ALDH1A1ATMCYP1A2 | |
| SCHEMBL15318695 | 0.83 | EPHX2 (0.39) | EPHX2ALDH1A1ATMTSHRTDP1 | |
| SCHEMBL15259142 | 0.83 | EPHX2 (0.39) | EPHX2ALDH1A1ATMTSHRTDP1 | |
| SCHEMBL10040088 | 0.82 | GRM4 (0.41) | EPHX2ALDH1A1TSHRTDP1CYP1A2 | |
| SCHEMBL9914758 | 0.82 | GRM4 (0.41) | EPHX2ALDH1A1TSHRTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646411-B1 | PREPARATION OF PET PRECURSOR | BLUE EARTH DIAGNOSTICS LTD (GB) | 2017-08-16 | — | — | EP | disclosed |
| US-9242924-B2 | Preparation of a 1-amino-3-hydroxy-cyclobutane-1-carboxylic acid derivative | GE HEALTHCARE LIMITED (GB) | 2016-01-26 | — | — | US | disclosed |
| EP-2758368-B1 | PREPARATION OF PET PRECURSOR | GE HEALTHCARE LTD (GB) | 2015-08-12 | — | — | EP | disclosed |
| WO-2012171941-A1 | PREPARATION OF PET PRECURSOR | GE HEALTHCARE LIMITED (GB) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012120025-A1 | PREPARATION OF A 1-AMINO-3-HYDROXY-CYCLOBUTANE-1-CARBOXYLIC ACID DERIVATIVE | GE HEALTHCARE LIMITED (GB) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012072567-A1 | PREPARATION OF PET PRECURSOR | GE HEALTHCARE LIMITED (GB) | 2012-06-07 | — | — | WO | disclosed |