Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31462441 | 1.00 | GAA (0.35) | GAAALOX15MGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL28715389 | 0.98 | GAA (0.34) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL24488794 | 0.85 | MGAM (0.31) | GAAMGAMSIMGAM2 | |
| SCHEMBL22945910 | 0.85 | MGAM (0.31) | GAAMGAMSIMGAM2 | |
| SCHEMBL9914600 | 0.85 | EPHX2 (0.38) | ALDH1A1CYP1A2ATMTSHR | |
| SCHEMBL13525934 | 0.85 | EPHX2 (0.38) | ALDH1A1CYP1A2ATMTSHR | |
| SCHEMBL10039979 | 0.85 | EPHX2 (0.38) | ALDH1A1CYP1A2ATMTSHR | |
| Hydrochloric Acid SCHEMBL28702703 | 0.84 | MGAM (0.30) | GAAMGAMSIMGAM2 | |
| SCHEMBL22946124 | 0.82 | ALDH1A1 (0.39) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL20605561 | 0.81 | ALOX15 (0.38) | GAAALOX15MGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008405-A1 | UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR | Taisho Pharmaceutical Co., Ltd. (JP) | 2022-06-08 | — | — | EP | disclosed |
| WO-2021020429-A1 | UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR | 大正製薬株式会社 | 2021-02-04 | — | — | WO | disclosed |