Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15275098 | 0.86 | CYP1A2 (0.31) | CYP1A2CYP3A4TSHRCLK4 | |
| SCHEMBL15868304 | 0.85 | POLB (0.42) | POLBMEN1NPC1ALDH1A1STAT3 | |
| SCHEMBL22901343 | 0.84 | POLB (0.42) | POLBMEN1NPC1ALDH1A1STAT3 | |
| SCHEMBL9914987 | 0.84 | AGPAT2 (0.35) | CYP1A2CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL14684622 | 0.84 | POLB (0.42) | POLBCYP1A2CYP3A4NPC1ALDH1A1 | |
| SCHEMBL29431642 | 0.84 | POLB (0.42) | POLBCYP1A2CYP3A4NPC1ALDH1A1 | |
| SCHEMBL14677434 | 0.84 | POLB (0.42) | POLBMEN1NPC1ALDH1A1STAT3 | |
| SCHEMBL23934201 | 0.83 | POLB (0.42) | POLBMEN1NPC1ALDH1A1STAT3 | |
| SCHEMBL116987 | 0.82 | POLB (0.42) | POLB | |
| SCHEMBL17609333 | 0.82 | POLB (0.40) | POLBMEN1NPC1ALDH1A1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646433-B1 | PYRIMIDINE COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-08-12 | — | — | EP | disclosed |
| US-9089136-B2 | Pyrimidine compound and use thereof for pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-07-28 | — | — | US | disclosed |
| US-20130252981-A1 | PYRIMIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-26 | — | — | US | disclosed |
| WO-2012074135-A1 | PYRIMIDINE COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252981-A1 | PYRIMIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | ZCCHC8, RRS1, HRH4 | POLB 1646/4885CYP1A2 386/4885CYP3A4 1237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.