Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | STK25 | O00506 | 1/20 | 0.32 |
| ▸ | CIT | O14578 | 1/20 | 0.32 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.32 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | PAK3 | O75914 | 1/20 | 0.32 |
| ▸ | STK10 | O94804 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14678192 | 0.88 | AGPAT2 (0.36) | AGPAT2HTR2BHTR6KITCNR2 | |
| SCHEMBL15275089 | 0.86 | KDM4E (0.37) | AGPAT2FGFR1KDM4ETP53TSHR | |
| SCHEMBL9914979 | 0.84 | POLB (0.42) | CYP3A4CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL14684635 | 0.84 | HTR2B (0.38) | AGPAT2HTR2BHTR6KITCNR2 | |
| SCHEMBL29431625 | 0.84 | HTR2B (0.38) | AGPAT2HTR2BHTR6KITCNR2 | |
| SCHEMBL15868318 | 0.83 | TYK2 (0.36) | AGPAT2HTR2BHTR6KITCNR2 | |
| SCHEMBL167348 | 0.82 | PDE10A (0.40) | AGPAT2HTR2BHTR6KITCNR2 | |
| SCHEMBL14677498 | 0.82 | AGPAT2 (0.33) | AGPAT2HTR2BHTR6KITCNR2 | |
| SCHEMBL19664210 | 0.82 | GRM2 (0.38) | AGPAT2HTR2BHTR6GRM2PIK3CA | |
| SCHEMBL15868314 | 0.80 | ACSS2 (0.36) | AGPAT2KITGRM2PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646433-B1 | PYRIMIDINE COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-08-12 | — | — | EP | disclosed |
| US-9089136-B2 | Pyrimidine compound and use thereof for pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-07-28 | — | — | US | disclosed |
| US-20130252981-A1 | PYRIMIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-26 | — | — | US | disclosed |
| WO-2012074135-A1 | PYRIMIDINE COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252981-A1 | PYRIMIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | ZCCHC8, RRS1, HRH4 | AGPAT2 3927/4885HTR2B 2655/4885HTR6 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.