SCHEMBL9915708

SCHEMBL9915708

C=CC(=O)Oc1ccc(-c2ccc(N(c3ccccc3)c3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.46
PDE6D O43924 1/20 0.43
TDP1 Q9NUW8 3/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
LMNA P02545 1/20 0.41
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
FABP7 O15540 1/20 0.39
FABP3 P05413 1/20 0.39
FABP5 Q01469 1/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP1A2 P05177 1/20 0.38
GAA P10253 1/20 0.38
CYP2C9 P11712 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2602449 1.00 THRB (0.46) THRBPDE6DTDP1ATML3MBTL1
SCHEMBL12751408 1.00 THRB (0.46) THRBPDE6DTDP1ATML3MBTL1
SCHEMBL9915707 0.98 THRB (0.47) THRBPDE6DTDP1ATML3MBTL1
SCHEMBL13777446 0.98 THRB (0.47) THRBPDE6DTDP1ATML3MBTL1
SCHEMBL172550 0.98 THRB (0.47) THRBPDE6DTDP1ATML3MBTL1
SCHEMBL11987036 0.98 THRB (0.47) THRBPDE6DTDP1ATML3MBTL1
SCHEMBL11987035 0.98 THRB (0.47) THRBPDE6DTDP1ATML3MBTL1
SCHEMBL12149005 0.98 THRB (0.47) THRBPDE6DTDP1ATML3MBTL1
SCHEMBL2609812 0.98 THRB (0.47) THRBPDE6DTDP1ATML3MBTL1
SCHEMBL10102824 0.98 THRB (0.47) THRBPDE6DTDP1ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10976677-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2021-04-13 US disclosed
US-10969703-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2021-04-06 US disclosed
US-20200218171-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2020-07-09 US disclosed
US-20200201200-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2020-06-25 US disclosed
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-20140030644-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2014-01-30 US disclosed
US-20140030644-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2014-01-30 US disclosed
US-20070059619-A1 Electrophotographic photoconductor, image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-20070059619-A1 Electrophotographic photoconductor, image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-20070042281-A1 Electrophotographic photoreceptor, and image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2007-02-22 US disclosed
US-20070042281-A1 Electrophotographic photoreceptor, and image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2007-02-22 US disclosed
US-7179573-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-20 US disclosed
US-7179573-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-20 US disclosed
US-7175957-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-7175957-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed