SCHEMBL9915757

SCHEMBL9915757

C=C(C)C(=O)Oc1ccc(/C=C/c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.44
LMNA P02545 2/20 0.44
KMT2A Q03164 3/20 0.43
MAPT P10636 3/20 0.43
CYP3A4 P08684 2/20 0.43
TP53 P04637 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
TTR P02766 1/20 0.43
RELA Q04206 2/20 0.42
ATM Q13315 1/20 0.42
MAOB P27338 2/20 0.40
MAOA P21397 1/20 0.40
PPARA Q07869 1/20 0.39
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23309765 1.00 ELANE (0.44) ELANELMNAKMT2AMAPTCYP3A4
SCHEMBL2609799 1.00 ELANE (0.44) ELANELMNAKMT2AMAPTCYP3A4
SCHEMBL12234109 0.91 LMNA (0.52) ELANELMNAKMT2AMAPTSMN1; SMN2
SCHEMBL9915685 0.91 LMNA (0.52) ELANELMNAKMT2AMAPTSMN1; SMN2
SCHEMBL10102835 0.89 ELANE (0.55) ELANELMNAKMT2AMAPTCYP3A4
SCHEMBL9915701 0.87 ELANE (0.48) ELANELMNAKMT2AMAPTSMN1; SMN2
SCHEMBL9915703 0.87 ELANE (0.48) ELANELMNAKMT2AMAPTSMN1; SMN2
SCHEMBL11987034 0.87 ELANE (0.48) ELANELMNAKMT2AMAPTSMN1; SMN2
SCHEMBL13051075 0.87 ELANE (0.48) ELANELMNAKMT2AMAPTSMN1; SMN2
SCHEMBL4403063 0.87 ELANE (0.48) ELANELMNAKMT2AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8197997-B2 Electrophotographic photoconductor, production method thereof, image forming method and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2012-06-12 US disclosed
US-8197997-B2 Electrophotographic photoconductor, production method thereof, image forming method and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2012-06-12 US disclosed
US-8114563-B2 Forming photosensitive layer on electroconductive substrate wherein the crosslinked surface layer has a surface roughness (Ra) not greater than 0.2 mu m and a peel strength not less than 0.2 N/mm; durability, stable electrical properties, good cleanability, and producing high-quality images RICOH COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-8114563-B2 Forming photosensitive layer on electroconductive substrate wherein the crosslinked surface layer has a surface roughness (Ra) not greater than 0.2 mu m and a peel strength not less than 0.2 N/mm; durability, stable electrical properties, good cleanability, and producing high-quality images RICOH COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-8097394-B2 Forming photosensitive layer on electroconductive substrate by spray coating using spray droplets having average diameter (D50) not greater than 10 mu m; abrasion resistance, stable electrical properties, durability RICOH COMPANY, LTD. (JP) 2012-01-17 US disclosed
US-8097394-B2 Forming photosensitive layer on electroconductive substrate by spray coating using spray droplets having average diameter (D50) not greater than 10 mu m; abrasion resistance, stable electrical properties, durability RICOH COMPANY, LTD. (JP) 2012-01-17 US disclosed
US-20090035672-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PRODUCTION METHOD THEREOF, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS USING PHOTOCONDUCTOR, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
US-20090035672-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PRODUCTION METHOD THEREOF, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS USING PHOTOCONDUCTOR, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
US-20080124638-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-05-29 US disclosed
US-20080124638-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-05-29 US disclosed
US-20080038649-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LIMITED (JP) 2008-02-14 US disclosed
US-20080038649-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LIMITED (JP) 2008-02-14 US disclosed
US-20070212627-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
US-20070212627-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed