SCHEMBL9915787

SCHEMBL9915787

C=CC(=O)OC(C)COc1ccc(CCc2ccc(N(c3ccc(C)cc3)c3ccc(-c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.41
FFAR1 O14842 3/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
FFAR4 Q5NUL3 2/20 0.35
ACACB O00763 1/20 0.35
LTB4R Q15722 1/20 0.35
LTB4R2 Q9NPC1 1/20 0.35
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12234063 0.97 THRB (0.44) THRBKMT2AMEN1ACACBLTB4R
SCHEMBL9915777 0.94 MAPT (0.37) THRBKMT2AMEN1ACACBALDH1A1
SCHEMBL9915767 0.94 MAPT (0.37) THRBKMT2AMEN1ACACBALDH1A1
SCHEMBL10083516 0.93 THRB (0.41) THRBFFAR1KMT2AMEN1ACACB
SCHEMBL9915779 0.91 HTT (0.39) THRBKMT2AMEN1ACACBALDH1A1
SCHEMBL11987108 0.91 HTT (0.39) THRBKMT2AMEN1ACACBALDH1A1
SCHEMBL13891694 0.91 HTT (0.39) THRBKMT2AMEN1ACACBALDH1A1
SCHEMBL9915785 0.88 THRB (0.44) THRBFFAR1KMT2AMEN1ACACB
SCHEMBL12751624 0.86 FFAR1 (0.39) FFAR1KMT2AMEN1FFAR4LTB4R
SCHEMBL9915765 0.85 MAPT (0.43) THRBFFAR1LTB4R2MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-20140030644-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2014-01-30 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-8383305-B2 Image forming apparatus RICOH COMPANY, LTD. (JP) 2013-02-26 US disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 US disclosed
US-20070172752-A1 IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2007-07-26 US disclosed
US-20070172752-A1 IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2007-07-26 US disclosed
US-20070154825-A1 Electrophotographic photoreceptor, method of image formation, image formation apparatus and process cartridge for image formation apparatus RICOH COMPANY, LTD. (JP) 2007-07-05 US disclosed
US-20070122724-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING PROCESS, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE FOR AN IMAGE FORMING APPARATUS USING THE SAME SUZUKI TETSURO 2007-05-31 US disclosed
US-20070059619-A1 Electrophotographic photoconductor, image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-20070042281-A1 Electrophotographic photoreceptor, and image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2007-02-22 US disclosed
US-7179573-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-20 US disclosed
US-7175957-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed