SCHEMBL9915818

SCHEMBL9915818

C=CC(=O)Oc1ccc(C(C)(c2ccc(OC(=O)C=C)cc2)c2ccc(N(c3ccc(C)cc3)c3ccc(-c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.43
LMNA P02545 1/20 0.37
LIPE Q05469 1/20 0.35
KIF11 P52732 1/20 0.35
RAB9A P51151 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MAPT P10636 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
PDE6D O43924 1/20 0.34
ALDH1A1 P00352 3/20 0.33
SRD5A1 P18405 2/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NPC1 O15118 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9915817 0.96 THRB (0.46) THRBLMNALIPERAB9AMEN1
SCHEMBL12149086 0.91 THRB (0.50) THRBLMNAMEN1KMT2AMAPT
SCHEMBL11938791 0.91 THRB (0.50) THRBLMNAMEN1KMT2AMAPT
SCHEMBL2540869 0.91 THRB (0.50) THRBLMNAMEN1KMT2AMAPT
SCHEMBL12149033 0.91 THRB (0.50) THRBLMNAMEN1KMT2AMAPT
SCHEMBL11987047 0.91 THRB (0.50) THRBLMNAMEN1KMT2AMAPT
SCHEMBL12149075 0.91 THRB (0.50) THRBLMNAMEN1KMT2AMAPT
SCHEMBL9915808 0.91 THRB (0.50) THRBLMNAMEN1KMT2AMAPT
SCHEMBL13051080 0.91 THRB (0.50) THRBLMNAMEN1KMT2AMAPT
SCHEMBL9915715 0.91 THRB (0.50) THRBLMNAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-8197997-B2 Electrophotographic photoconductor, production method thereof, image forming method and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2012-06-12 US disclosed
US-8197997-B2 Electrophotographic photoconductor, production method thereof, image forming method and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2012-06-12 US disclosed
US-8114563-B2 Forming photosensitive layer on electroconductive substrate wherein the crosslinked surface layer has a surface roughness (Ra) not greater than 0.2 mu m and a peel strength not less than 0.2 N/mm; durability, stable electrical properties, good cleanability, and producing high-quality images RICOH COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-8114563-B2 Forming photosensitive layer on electroconductive substrate wherein the crosslinked surface layer has a surface roughness (Ra) not greater than 0.2 mu m and a peel strength not less than 0.2 N/mm; durability, stable electrical properties, good cleanability, and producing high-quality images RICOH COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-8097394-B2 Forming photosensitive layer on electroconductive substrate by spray coating using spray droplets having average diameter (D50) not greater than 10 mu m; abrasion resistance, stable electrical properties, durability RICOH COMPANY, LTD. (JP) 2012-01-17 US disclosed
US-8097394-B2 Forming photosensitive layer on electroconductive substrate by spray coating using spray droplets having average diameter (D50) not greater than 10 mu m; abrasion resistance, stable electrical properties, durability RICOH COMPANY, LTD. (JP) 2012-01-17 US disclosed
US-7855040-B2 Method for preparing photoreceptor, photoreceptor prepared by the method, and image forming method and apparatus and process cartridge using the photoreceptor RICOH COMPANY LIMITED (JP) 2010-12-21 US disclosed
US-20090035672-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PRODUCTION METHOD THEREOF, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS USING PHOTOCONDUCTOR, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
US-20090035672-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PRODUCTION METHOD THEREOF, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS USING PHOTOCONDUCTOR, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
US-20080138725-A1 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY LIMITED (JP) 2008-06-12 US disclosed
US-20080124638-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-05-29 US disclosed
US-20080124638-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-05-29 US disclosed
US-20080102391-A1 METHOD FOR PREPARING PHOTORECEPTOR, PHOTORECEPTOR PREPARED BY THE METHOD, AND IMAGE FORMING METHOD AND APPARATUS AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR RICOH COMPANY LIMITED (JP) 2008-05-01 US disclosed
US-20080038649-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LIMITED (JP) 2008-02-14 US disclosed
US-20080038649-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LIMITED (JP) 2008-02-14 US disclosed
US-20070212627-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
US-20070212627-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed