Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | CHKA | P35790 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915623 | 0.83 | KDM4A (0.49) | ALDH1A1GFER | |
| SCHEMBL7717422 | 0.83 | KDM4A (0.49) | ALDH1A1GFER | |
| SCHEMBL3221096 | 0.79 | ALDH1A1 (0.54) | AOC3CHKATDP1CALM1ALDH1A1 | |
| SCHEMBL9915874 | 0.76 | CHKA (0.41) | AOC3CHKACNR2TDP1KDM4E | |
| SCHEMBL3868886 | 0.75 | TSHR (0.52) | CNR2TDP1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL11478854 | 0.75 | ALDH1A1 (0.61) | AOC3CNR2TDP1KDM4EALDH1A1 | |
| SCHEMBL13223079 | 0.75 | ESRRG (0.48) | AOC3CNR2 | |
| SCHEMBL2206611 | 0.74 | ALDH1A1 (0.58) | CHKATDP1KDM4ECALM1ALDH1A1 | |
| SCHEMBL4407612 | 0.74 | AOC3 (0.59) | AOC3CNR2TDP1KDM4EALDH1A1 | |
| SCHEMBL4405018 | 0.74 | ALDH1A1 (0.70) | CHKATDP1CALM1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |