SCHEMBL9916080

SCHEMBL9916080

CCC(C)(C)C(=O)N1C(=O)CC1OC(C)=O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 8/20 0.52
POLB P06746 1/20 0.34
FKBP1A P62942 2/20 0.32
ELANE P08246 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9916078 0.87 RIPK1 (0.51) RIPK1FKBP1AELANE
SCHEMBL9916085 0.84 RIPK1 (0.49) RIPK1FKBP1A
SCHEMBL9916087 0.84 RIPK1 (0.49) RIPK1FKBP1A
SCHEMBL12015354 0.84 POLB (0.38) RIPK1POLBELANE
SCHEMBL9916082 0.83 RIPK1 (0.36) RIPK1POLB
SCHEMBL9916091 0.82 RIPK1 (0.47) RIPK1POLBFKBP1A
SCHEMBL9917117 0.81 RIPK1 (0.35) RIPK1
SCHEMBL9916098 0.81 RIPK1 (0.38) RIPK1
SCHEMBL9916095 0.81 RIPK1 (0.46) RIPK1POLBFKBP1A
SCHEMBL9916104 0.79 RIPK1 (0.36) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8859183-B2 N-acyl-β-lactam derivative, macromolecular compound, and photoresist composition KURARAY CO., LTD. (JP) 2014-10-14 US disclosed
US-8753794-B2 N-acyl-β-lactam derivative, macromolecular compound, and photoresist composition KURARAY CO., LTD. (JP) 2014-06-17 US disclosed
US-20140038106-A1 N-ACYL-B-LACTAM DERIVATIVE, MACROMOLECULAR COMPOUND, AND PHOTORESIST COMPOSITION KURARAY CO., LTD. (JP) 2014-02-06 US disclosed
US-20120148954-A1 N-ACYL-B-LACTAM DERIVATIVE, MACROMOLECULAR COMPOUND, AND PHOTORESIST COMPOSITION KURARAY CO., LTD. (JP) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120148954-A1 N-ACYL-B-LACTAM DERIVATIVE, MACROMOLECULAR COMPOUND, AND PHOTORESIST COMPOSITION COASY, ARCN1, CLTB RIPK1 2490/4885POLB 486/4885FKBP1A 461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.