Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18561575 | 0.88 | CYP19A1 (0.45) | CYP19A1EPHX2CYP17A1NPSR1TSHR | |
| SCHEMBL951987 | 0.87 | CYP19A1 (0.49) | CYP19A1EPHX2CYP17A1NPSR1TSHR | |
| SCHEMBL27436848 | 0.84 | CYP19A1 (0.53) | CYP19A1EPHX2CYP17A1NPSR1TSHR | |
| SCHEMBL9852706 | 0.83 | EPHX2 (0.51) | CYP19A1EPHX2CYP17A1NPSR1TSHR | |
| SCHEMBL14510687 | 0.81 | CYP19A1 (0.50) | CYP19A1EPHX2CYP17A1NPSR1TSHR | |
| SCHEMBL18826687 | 0.81 | CYP19A1 (0.50) | CYP19A1EPHX2CYP17A1NPSR1TSHR | |
| SCHEMBL158814 | 0.81 | CYP19A1 (0.50) | CYP19A1EPHX2CYP17A1NPSR1TSHR | |
| SCHEMBL3212895 | 0.81 | CYP19A1 (0.50) | CYP19A1EPHX2CYP17A1NPSR1TSHR | |
| SCHEMBL3902972 | 0.81 | CYP19A1 (0.50) | CYP19A1EPHX2CYP17A1NPSR1TSHR | |
| SCHEMBL5988511 | 0.81 | CYP19A1 (0.50) | CYP19A1EPHX2CYP17A1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417794-A | Preparation method of saxagliptin intermediate | 扬州市三药制药有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-115417794-A | Preparation method of saxagliptin intermediate | 扬州市三药制药有限公司 | 2022-12-02 | — | — | CN | disclosed |
| EP-3618833-B1 | TRIPARTITE ANDROGEN RECEPTOR ELIMINATORS, METHODS AND USES THEREOF | SPG THERAPEUTICS INC (US) | 2022-01-19 | — | — | EP | disclosed |
| US-20200207753-A1 | Tripartite Androgen Receptor Eliminators, Methods and Uses Thereof | SPG THERAPEUTICS, INC. (US) | 2020-07-02 | — | — | US | disclosed |
| EP-2353048-B1 | PATTERN FORMING METHOD USING DEVELOPER CONTAINING ORGANIC SOLVENT AND RINSING SOLUTION FOR USE IN THE PATTERN FORMING METHOD | FUJIFILM CORP (JP) | 2015-02-25 | — | — | EP | disclosed |
| US-20120148954-A1 | N-ACYL-B-LACTAM DERIVATIVE, MACROMOLECULAR COMPOUND, AND PHOTORESIST COMPOSITION | KURARAY CO., LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
| US-20110117497-A1 | ACRYLATE DERIVATIVE, HALOESTER DERIVATIVE, POLYMER COMPOUND AND PHOTORESIST COMPOSITION | KURARAY CO., LTD. (JP) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207753-A1 | Tripartite Androgen Receptor Eliminators, Methods and Uses Thereof | AR, ESRRA, ESRRB | CYP19A1 34/4885EPHX2 1265/4885CYP17A1 10/4885 |
| US-20120148954-A1 | N-ACYL-B-LACTAM DERIVATIVE, MACROMOLECULAR COMPOUND, AND PHOTORESIST COMPOSITION | COASY, ARCN1, CLTB | CYP19A1 627/4885EPHX2 4538/4885CYP17A1 1936/4885 |
| US-20110117497-A1 | ACRYLATE DERIVATIVE, HALOESTER DERIVATIVE, POLYMER COMPOUND AND PHOTORESIST COMPOSITION | ARCN1, H1-10, RER1 | CYP19A1 2519/4885EPHX2 2407/4885CYP17A1 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.