SCHEMBL991743

SCHEMBL991743

NCCCOCC(COCCCN)OCCCN

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.48
TLR2 O60603 8/20 0.42
LPAR1 Q92633 4/20 0.42
LPAR3 Q9UBY5 4/20 0.42
LPAR2 Q9HBW0 1/20 0.42
DNM1 Q05193 1/20 0.40
ODC1 P11926 1/20 0.38
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17086768 0.91 CYP3A4 (0.56) CYP3A4TLR2LPAR1LPAR3LPAR2
SCHEMBL12317022 0.91 CYP3A4 (0.46) CYP3A4TLR2LPAR1LPAR3LPAR2
SCHEMBL16807613 0.91 TLR2 (0.46) CYP3A4TLR2LPAR1LPAR3LPAR2
SCHEMBL12317008 0.89 CYP3A4 (0.44) CYP3A4TLR2LPAR1LPAR3LPAR2
SCHEMBL11302498 0.88 DNM1 (0.60) CYP3A4TLR2LPAR1LPAR3LPAR2
SCHEMBL11304818 0.88 DNM1 (0.60) CYP3A4TLR2LPAR1LPAR3LPAR2
SCHEMBL6914579 0.87 CYP3A4 (0.56) CYP3A4TLR2LPAR1LPAR3LPAR2
Hydrochloric Acid SCHEMBL11301980 0.86 DNM1 (0.63) CYP3A4TLR2LPAR1LPAR3LPAR2
SCHEMBL25622597 0.85 CYP3A4 (0.42) CYP3A4TLR2LPAR1LPAR3LPAR2
SCHEMBL11154491 0.85 TLR2 (0.46) CYP3A4TLR2LPAR1LPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4332928-A EPOXY RESIN CURING AGENTS MILLIKEN RESEARCH CORPORATION (US) 1982-06-01 US claimed
US-9714339-B2 Rubber composition comprising an epoxy resin and a polyimine hardener COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-07-25 US disclosed
US-9663633-B2 Composition based on natural rubber and on a polyaldimine compound COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-05-30 US disclosed
US-9441083-B2 Functional polymer membrane and method of producing the same FUJIFILM CORPORATION (JP) 2016-09-13 US disclosed
EP-2451656-B1 composition based on natural rubber and a polyimine compound MICHELIN & CIE (FR) 2015-11-25 EP disclosed
US-20150259488-A1 FUNCTIONAL POLYMER MEMBRANE AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2015-09-17 US disclosed
US-20150183983-A1 RUBBER COMPOSITION COMPRISING AN EPOXY RESIN AND A POLYIMINE HARDENER MICHELIN RECHERCHE ET TECHNIQUE, S.A. (CH) 2015-07-02 US disclosed
EP-2877526-A1 RUBBER COMPOSITION COMPRISING AN EPOXY RESIN AND A POLYIMINE HARDENER Compagnie Générale des Etablissements Michelin (FR) 2015-06-03 EP disclosed
US-9006321-B2 Composition made from natural rubber and a polyimine compound COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-04-14 US disclosed
EP-2451658-B1 COMPOSITION MADE FROM NATURAL RUBBER AND A POLYIMINE COMPOUND MICHELIN & CIE (FR) 2014-09-10 EP disclosed
EP-1032606-B1 SUPERABSORBING COMPOSITIONS AND PROCESSES FOR PREPARING SAME SOLUTIA INC (US) 2003-03-26 EP disclosed
EP-0998599-B1 SUPERABSORBING FIBERS AND FILMS AND PROCESS FOR PREPARING SAME SOLUTIA INC (US) 2003-03-12 EP disclosed
EP-0970139-B1 FORMING CROSSLINKED POLYSUCCINIMIDE SOLUTIA INC (US) 2002-06-26 EP disclosed
US-6150495-A IMIDIDATION, HYDROLYSIS, CROSSLINKING AND DRAWING TO FORM FIBERS SOLUTIA INC. (US) 2000-11-21 US disclosed
US-6027804-A Superabsorbing compositions and processes for preparing same SOLUTIA INC. (US) 2000-02-22 US disclosed
US-5834568-A Forming crosslinked polysuccinimide SOLUTIA, INC. (US) 1998-11-10 US disclosed
EP-0074707-A2 Polyamines and their use as curing agents MILLIKEN RESEARCH CORPORATION (US) 1983-03-23 EP disclosed
US-4362856-A CURING AGENT FOR EPOXY RESINS MILLIKEN RESEARCH CORPORATION (US) 1982-12-07 US disclosed
US-4351934-A Epoxy resin compositions MILLIKEN RESEARCH CORPORATION (US) 1982-09-28 US disclosed
US-4332928-A EPOXY RESIN CURING AGENTS MILLIKEN RESEARCH CORPORATION (US) 1982-06-01 US disclosed